It is well-known that the interaction of both genetic and epigenetic mechanisms results in the
formation of malignant tumor. Epigenetic mechanism includes DNA methylation, histone …

Introduction 3. DNA methylation in prostate cancer 3.1. DNA Hypermethylation 3.1. 1.
Hormonal response genes 3.1. 2. Cell cycle control genes 3.1. 3. Tumor invasion and tumor …

The genome contains information in two forms, genetic and epigenetic. The genetic
information is stored in each cell in the form of DNA as genetic code, that provides the …

Somatic epigenetic alterations include DNA methylation, histone modification, RNA
interference, disordered micro-RNA gene expression and genomic imprinting among others …

Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

There is increasing evidence that DNA methylation is a critical source of gene regulation. In
addition, interindividual differences in DNA methylation status in cancer related genes are …

The prostate gland is the most common site of cancer and the second leading cause of
cancer death in American men. Recent emerging molecular biological technologies help us …

Prostate cancer (PCa) is the most prevalent cancer, a significant contributor to morbidity and
a leading cause of cancer-related death in men in Western industrialized countries. In …

Prostate cancer is the most common malignancy and the second leading cause of cancer
death among men in the United States. There are three well-established risk factors for …