Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia
Y Chalandon, X Thomas, S Hayette… - Blood, The Journal …, 2015 - ashpublications.org
In this study, we randomly compared high doses of the tyrosine kinase inhibitor imatinib
combined with reduced-intensity chemotherapy (arm A) to standard imatinib/hyperCVAD …
combined with reduced-intensity chemotherapy (arm A) to standard imatinib/hyperCVAD …
[HTML][HTML] A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study
S Chiaretti, A Vitale, M Vignetti, A Piciocchi, P Fazi… - …, 2016 - ncbi.nlm.nih.gov
In the GIMEMA LAL 0904 protocol, adult Philadelphia positive acute lymphoblastic leukemia
patients were treated with chemotherapy for induction and consolidation, followed by …
patients were treated with chemotherapy for induction and consolidation, followed by …
Clinical effect of imatinib added to intensive combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
KH Lee, JH Lee, SJ Choi, M Seol, YS Lee, WK Kim… - Leukemia, 2005 - nature.com
Clinical impact of imatinib was evaluated in 20 patients (median age, 37 years; range, 15–
67 years) with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic …
67 years) with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic …
Chemotherapy-phased imatinib pulses improve long-term outcome of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: Northern …
R Bassan, G Rossi, EM Pogliani, E Di Bona… - Journal of Clinical …, 2010 - ascopubs.org
Purpose Short imatinib pulses were added to chemotherapy to improve the long-term
survival of adult patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic …
survival of adult patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic …
Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of …
A de Labarthe, P Rousselot, F Huguet-Rigal… - Blood, 2007 - ashpublications.org
The combination of imatinib with chemotherapy has been recently reported as very
promising in patients with Philadelphia chromosome–positive (Ph+) acute lymphoblastic …
promising in patients with Philadelphia chromosome–positive (Ph+) acute lymphoblastic …
Pre-transplant imatinib-based therapy improves the outcome of allogeneic hematopoietic stem cell transplantation for BCR–ABL-positive acute lymphoblastic …
A high complete remission (CR) rate has been reported in newly diagnosed Philadelphia
chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) following imatinib-based …
chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) following imatinib-based …
UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia
AK Fielding, JM Rowe, G Buck, L Foroni… - Blood, The Journal …, 2014 - ashpublications.org
The Philadelphia chromosome positive arm of the UKALLXII/ECOG2993 study for adult
acute lymphoblastic leukemia (ALL) enrolled 266 patients between 1993 and 2003 (pre …
acute lymphoblastic leukemia (ALL) enrolled 266 patients between 1993 and 2003 (pre …
[HTML][HTML] Concurrent intensive chemotherapy and imatinib before and after stem cell transplantation in newly diagnosed Philadelphia chromosome-positive acute …
JM Ribera, A Oriol, M González, B Vidriales… - …, 2010 - ncbi.nlm.nih.gov
Background Imatinib, given concurrently or alternating with chemotherapy, has improved the
response and survival of patients with Philadelphia chromosome-positive acute …
response and survival of patients with Philadelphia chromosome-positive acute …
Dasatinib/prednisone induction followed by blinatumomab/dasatinib in Ph+ acute lymphoblastic leukemia
AS Advani, A Moseley, KM O'Dwyer, BL Wood… - Blood …, 2023 - ashpublications.org
Novel treatment strategies are needed for the treatment of Philadelphia chromosome–
positive (Ph+) acute lymphoblastic leukemia (ALL) in older patients. This trial evaluated the …
positive (Ph+) acute lymphoblastic leukemia (ALL) in older patients. This trial evaluated the …
Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)
B Wassmann, H Pfeifer, N Goekbuget, DW Beelen… - Blood, 2006 - ashpublications.org
The best strategy for incorporating imatinib in front-line treatment of Ph+ acute lymphoblastic
leukemia (ALL) has not been established. We enrolled 92 patients with newly diagnosed …
leukemia (ALL) has not been established. We enrolled 92 patients with newly diagnosed …