The pros and cons of motor, memory, and emotion-related behavioral tests in the mouse traumatic brain injury model

R Zhang, J Wang, L Huang, TJ Wang… - Neurological …, 2022 - Taylor & Francis
Traumatic brain injury (TBI) is a medical emergency with high morbidity and mortality. Motor,
memory, and emotion-related deficits are common symptoms following TBI, yet treatment is …

Clinical relevance of behavior testing in animal models of traumatic brain injury

SR Shultz, SJ McDonald, F Corrigan… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of morbidity worldwide, with patients often
suffering from consequences such as cognitive deficits, social abnormalities, anxiety …

Motor and cognitive function evaluation following experimental traumatic brain injury

ST Fujimoto, L Longhi, KE Saatman… - … & biobehavioral reviews, 2004 - Elsevier
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …

[HTML][HTML] Traumatic brain injury–modeling neuropsychiatric symptoms in rodents

O Malkesman, LB Tucker, J Ozl, JT McCabe - Frontiers in neurology, 2013 - frontiersin.org
Each year in the US,∼ 1.5 million people sustain a traumatic brain injury (TBI). Victims of TBI
can suffer from chronic post-TBI symptoms, such as sensory and motor deficits, cognitive …

Traumatic brain injury in animal models and humans

H Adwanikar, L Noble-Haeusslein, HS Levin - Animal Models of …, 2011 - Springer
Clinical/behavioral measures have traditionally been used to assess neurologic outcomes
after human traumatic brain injury (TBI) as well as in experimental models of TBI. In this …

Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury

Z Zhao, DJ Loane, MG Murray, BA Stoica… - Journal of …, 2012 - liebertpub.com
Controlled cortical impact injury (CCI) is a widely-used, clinically-relevant model of traumatic
brain injury (TBI). Although functional outcomes have been used for years in this model, little …

The revised neurobehavioral severity scale (NSS‐R) for rodents

AM Yarnell, ES Barry, A Mountney… - Current protocols in …, 2016 - Wiley Online Library
Motor and sensory deficits are common following traumatic brain injury (TBI). Although
rodent models provide valuable insight into the biological and functional outcomes of TBI …

Detecting behavioral deficits in rats after traumatic brain injury

N Hausser, K Johnson, MA Parsley, J Guptarak… - JoVE (Journal of …, 2018 - jove.com
With the increasing incidence of traumatic brain injury (TBI) in both civilian and military
populations, TBI is now considered a chronic disease; however, few studies have …

[HTML][HTML] Measuring anxiety-like behaviors in rodent models of traumatic brain injury

LB Tucker, JT McCabe - Frontiers in behavioral neuroscience, 2021 - frontiersin.org
Anxiety is a common complaint following acquired traumatic brain injury (TBI). However, the
measurement of dysfunctional anxiety behavioral states following experimental TBI in …

[HTML][HTML] The nanotheranostic researcher's guide for use of animal models of traumatic brain injury

BZ McDonald, CC Gee, FM Kievit - Journal of nanotheranostics, 2021 - mdpi.com
Traumatic brain injury (TBI) is currently the leading cause of injury-related morbidity and
mortality worldwide, with an estimated global cost of USD 400 billion annually. Both clinical …