Background and Objective Serotonin levels are increased in acute appendicitis. We
investigated the possible source of this increase. The aim of this study was to compare the …

The appendix is lined by a mucosa which has many neuroendocrine cells containing
serotonin. Local release of serotonin can act as a mediator of inflammation. In this study we …

Background: Mast cells play an important role in various inflammatory and immune reaction.
Mast cells are constantly present in the appendices, and appendix remains one of the …

Aim and objective: To study the number and distribution of mast cells in surgically resected
appendices of normal and inflamed, age and sex wise. Introduction: Mast cells play an …

Mast cells are known to be effector cells in various inflammatory reactions, but their role in
appendicitis is unclear. The present study was undertaken to investigate the extent of mast …

Appendectomy specimens due to acute appendicitis are among the most common surgical
resection specimens. The hallmark histologic finding of acute appendicitis is neutrophilic …

Aim and objective-1) To identify and quantify the mast cells in surgically resected inflamed
appendices. 2) To assess the role of mast cells in the pathogenesis of acute appendicitis. 3) …

Background Due to lack of reliable biochemical/radiological markers, the diagnosis of acute
appendicitis is based only on clinical features. Methods We estimated plasma serotonin …

Background/aims: In the gastrointestinal system, the relationship between the enteric
nervous system and mast cells has been described in normal and pathological conditions …

Objectives: The mast cell remains an enigmatic cell, found resident in tissues throughout the
body particularly in association with structures such as blood vessels and nerves. Various …