Tyrosinase inhibitors improve skin whitening by inhibiting the formation of melanin
precursors in the skin. The inhibitory activity of seven phlorotannins (1–7), triphlorethol A (1) …

Extracts from seventeen seaweeds were determined for tyrosinase inhibitory activity using
mushroom tyrosinase with L-tyrosine as a substrate. Only one of them, Ecklonia stolonifera …

Compounds were isolated from Ecklonia stolonifera Okamura, a marine brown alga widely
consumed as food. Among the isolated compounds, 974-A was demonstrated for the first …

Background Abnormal deposition of melanin may cause an aesthetic skin problem;
therefore, the control of unwanted excessive melanin synthesis is the major goal of cosmetic …

Tyrosinase inhibition may be a means to alleviate not only skin hyperpigmentation but also
neurodegeneration associated with Parkinson's disease. In the course of metabolite …

In this study, to assess the feasibility of phlorotannins isolated from Ecklonia cava as an
inhibitor of melanin formation, we evaluated its inhibitory effects on mushroom tyrosinase …

Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasama …

Nontoxic natural products useful in skin care cosmetics are of considerable interest.
Tyrosinase is a rate-limiting enzyme for which its inhibitor is useful in developing whitening …

BACKGROUND: Tyrosinase inhibitors have become increasingly important because of their
ability to inhibit the synthesis of the pigment melanin. A search for new agents with strong …

Tyrosinase plays an important role in the process of melanin biosynthesis, and it is a
biochemical target enzyme for skin-whitening agents and the remedy for disturbances in …