[HTML][HTML] Multiple stressors in the environment: the effects of exposure to an antidepressant (venlafaxine) and increased temperature on zebrafish metabolism

H Mehdi, LM Bragg, MR Servos, PM Craig - Frontiers in Physiology, 2019 - frontiersin.org
Aquatic organisms are continuously exposed to multiple environmental stressors working
cumulatively to alter ecosystems. Wastewater-dominated environments are often riddled by …

Interactive effects of venlafaxine and thermal stress on zebrafish (Danio rerio) inflammatory and heat shock responses

AV Weber, BL Firth, IG Cadonic, PM Craig - Comparative Biochemistry and …, 2023 - Elsevier
Venlafaxine (VFX), a commonly prescribed antidepressant often detected in wastewater
effluent, and acute temperature elevations from climate change and increased urbanization …

Zygotic exposure to venlafaxine disrupts cortisol stress axis activity in multiple generations of zebrafish

WA Thompson, MM Vijayan - Environmental Pollution, 2021 - Elsevier
Ubiquitous use of antidepressants has resulted in increased concentrations of these
pharmaceuticals in waterways receiving municipal wastewater effluent. Amongst these …

The antidepressant venlafaxine disrupts brain monoamine levels and neuroendocrine responses to stress in rainbow trout

N Melnyk-Lamont, C Best, M Gesto… - … science & technology, 2014 - ACS Publications
Venlafaxine, a serotonin–norepinephrine reuptake inhibitor, is a widely prescribed
antidepressant drug routinely detected in the aquatic environment. However, little is known …

Environmental levels of the antidepressant venlafaxine impact the metabolic capacity of rainbow trout

C Best, N Melnyk-Lamont, M Gesto, MM Vijayan - Aquatic toxicology, 2014 - Elsevier
The antidepressant venlafaxine is detected at parts per billion levels in tertiary-treated
municipal wastewater effluent. However, the impact of this serotonin–norepinephrine …

Differential behavioural responses to venlafaxine exposure route, warming and acidification in juvenile fish (Argyrosomus regius)

AL Maulvault, LH Santos, JR Paula, C Camacho… - Science of the Total …, 2018 - Elsevier
Antidepressants, such as venlafaxine (VFX), which are considered emerging environmental
pollutants, are increasingly more present in the marine environment, and recent evidence …

Investigating wastewater treatment plant effluent and pharmaceutical exposure on innate cytokine expression of darters (Etheostoma spp.) in the Grand River …

RE Dawe, LM Bragg, HA Dhiyebi, MR Servos… - … and Physiology Part B …, 2024 - Elsevier
Fish live in continuous contact with various stressors and antigenic material present within
their environments. The impact of stressors associated with wastewater-exposed …

[HTML][HTML] Sex-specific and long-term impacts of early-life venlafaxine exposure in zebrafish

WA Thompson, Z Shvartsburd, MM Vijayan - Biology, 2022 - mdpi.com
Simple Summary Excessive use of antidepressants, combined with our inability to
completely clear them from municipal wastewater effluents, has led to their increased …

[HTML][HTML] Diazepam and fluoxetine decrease the stress response in zebrafish

MS Abreu, G Koakoski, D Ferreira, TA Oliveira… - PloS one, 2014 - journals.plos.org
The presence of pharmaceutical products in the aquatic environment has been reported in
several studies. However, the impact of these drugs on living organisms is still …

Living in a multi-stressors environment: An integrated biomarker approach to assess the ecotoxicological response of meagre (Argyrosomus regius) to venlafaxine …

AL Maulvault, C Camacho, V Barbosa, R Alves… - Environmental …, 2019 - Elsevier
Pharmaceuticals, such as the antidepressant venlafaxine (VFX), have been frequently
detected in coastal waters and marine biota, and there is a growing body of evidence that …