The polarization of macrophages into a regulatory-like phenotype and the production of IL-
10 plays an important role in the resolution of inflammation. We show in this study that PGE …

Interleukin‐23, a recently described cytokine produced by activated antigen‐presenting
cells, including dendritic cells, is a p19/p40 heterodimer. The p40 subunit is shared with IL …

Exposure to pathogens induces antigen-presenting cells (APC) such as macrophages and
dendritic cells (DC) to produce various endogenous mediators, including arachidonic acid …

Summary Interleukin‐10 (IL‐10) is an immunosuppressive cytokine that inhibits
inflammatory gene expression. Phosphatidylinositol 3‐kinase (PI3K)‐mediated signalling …

Dendritic cells (DCs) are central players in coordinating immune responses, both innate and
adaptive. While the role of lipid mediators in the immune response has been the subject of …

The role of CREB in LPS signaling is controversial. The objective of this study was to
evaluate the effect of LPS on phosphorylation and transcriptional activation of CREB, in …

Recognition of bacterial constituents by mast cells (MCs) is dependent on the presence of
pattern recognition receptors, such as Toll-like receptors (TLRs). The final cellular response …

Stimulation of human monocyte-derived dendritic cells with the yeast extract zymosan is
characterized by a predominant production of IL-10 and a strong induction of …

Interleukin-10 (IL-10), a pleiotropic cytokine that inhibits inflammatory and cell-mediated
immune responses, is produced by a wide variety of cell types including T and B cells and …

IL-10 regulates anti-inflammatory signaling via the activation of STAT3, which in turn controls
the induction of a gene expression program whose products execute inhibitory effects on …