Cephalosporins (third-and higher-generation) and carbapenems are critically important
antimicrobials for human medicine since in some instances, they are either the sole or one …

The studies included the present PhD Thesis have been published in the following scientific
journal papers, which are cited in the text by Roman numerals as follows: I. Tello, M., Ocejo …

Since the time of Galen and Hippocrates, medicine has had a slow progression, with each
new advance improving the length and quality of patients' lives. By the nineteenth century …

Extended-Spectrum-Cephalosporin (ESC)-resistant Enterobacteriaceae have widely spread
in all settings worldwide. In animals, Extended-Spectrum Beta-Lactamase (ESBL) producers …

The goals of medicine have mostly aimed at relieving pain and suffering, promoting health
and preventing diseases, as well as curing diseases when possible and providing care …

A longitudinal study was designed in five dairy cattle farms to assess the within-farm
dynamics of ESBL-/AmpC-/carbapenemase-producing E. coli and their resistance profiles …

Objectives To explore the dynamics of faecal ESBL/AmpC shedding in dairy cattle and
farmers, a study was conducted to examine changes in shedding by individual animals, as …

The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …

Multidrug-resistant bacteria pose a significant threat to global public health (World Health
Organization, 2017; Centers for Disease Control and Prevention, 2020). In this context …

Antimicrobial resistance can be effectively limited by improving the judicious use of
antimicrobials in food production. However, its effect on the spread of AMR genes in animal …