[HTML][HTML] Tumor-derived extracellular vesicles activate normal human fibroblasts to a cancer-associated fibroblast-like phenotype, sustaining a pro-tumorigenic …

I Giusti, M Di Francesco, G Poppa, L Esposito… - Frontiers in …, 2022 - frontiersin.org
Fibroblasts in the tumor microenvironment have been proven to actively participate in tumor
progression; they can be “educated” by cancer cells acquiring an activated state and, as …

Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention

F Wendler, R Favicchio, T Simon, C Alifrangis… - Oncogene, 2017 - nature.com
Intercellular communication sets the pace for transformed cells to survive and to thrive.
Extracellular vesicles (EVs), such as exosomes, microvesicles and large oncosomes, are …

Ovarian cancer-derived extracellular vesicles affect normal human fibroblast behavior

I Giusti, M Di Francesco, S D'Ascenzo… - Cancer biology & …, 2018 - Taylor & Francis
It has become clear that non-tumor cells in the microenvironment, especially fibroblasts,
actively participate in tumor progression. Fibroblasts conditioned by tumor cells become …

Extracellular vesicles: Their role in cancer biology and epithelial–mesenchymal transition

SK Gopal, DW Greening, A Rai, M Chen… - Biochemical …, 2017 - portlandpress.com
Cell–cell communication is critical across an assortment of physiological and pathological
processes. Extracellular vesicles (EVs) represent an integral facet of intercellular …

[HTML][HTML] Landscape of extracellular vesicles in the tumour microenvironment: Interactions with stromal cells and with non-cell components, and impacts on metabolic …

DX Zhang, LT Vu, NN Ismail, MTN Le… - Seminars in cancer …, 2021 - Elsevier
Extracellular vesicles (EVs) are increasingly recognised as a pivotal player in cell-cell
communication, an attribute of EVs that derives from their ability to transport bioactive …

[HTML][HTML] Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts

C Li, C Sun, W Lohcharoenkal, MM Ali, P Xing… - Cell death …, 2023 - nature.com
Cutaneous squamous cell carcinoma (cSCC) is a fast-increasing cancer with metastatic
potential. Extracellular vesicles (EVs) are small membrane-bound vesicles that play …

[HTML][HTML] Extracellular vesicles in the tumor microenvironment: old stories, but new tales

L Han, EWF Lam, Y Sun - Molecular cancer, 2019 - Springer
Mammalian cells synthesize and release heterogeneous extracellular vesicles (EVs) which
can be generally recognized as subclasses including exosomes, microvesicles (MVs), and …

[HTML][HTML] The role of cancer-associated fibroblasts and extracellular vesicles in tumorigenesis

I Shoucair, F Weber Mello, J Jabalee, S Maleki… - International Journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) play a key role in the communication between cancer cells and
stromal components of the tumor microenvironment (TME). In this context, cancer cell …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

Extracellular vesicles and their roles in cancer progression

WH Chang, RA Cerione, MA Antonyak - Cancer cell signaling: Methods …, 2021 - Springer
Extracellular vesicles (EVs) produced by cancer cells function as a unique form of
intercellular communication that can promote cell growth and survival, help shape the tumor …