Recent investigations have revealed 1) that the isochores of the human genome group into
two super‐families characterized by two different long‐range 3D structures, and 2) that these …

Recent investigations have shown that isochores are characterized by a 3-D structure which
is primarily responsible for the topology of chromatin domains. More precisely, an analysis of …

The chromatin of the human genome was analyzed at three DNA size levels. At the first,
compartment level, two “gene spaces” were found many years ago: A GC-rich, gene-rich …

How the same DNA sequences can function in the three-dimensional architecture of
interphase nucleus, fold in the very compact structure of metaphase chromosomes, and go …

A key feature of interphase chromosomes is their compaction into discrete “territories” in the
nucleus. In this review, we focus on the compartmentalization of the genome conferred by …

How the same DNA sequences can function in the three-dimensional architecture of
interphase nucleus, fold in the very compact structure of metaphase chromosomes and go …

A recent investigation showed the existence of correlations between the architectural
features of mammalian interphase chromosomes and the compositional properties of …

Mitotic chromosomes are essential structures for the faithful transmission of duplicated
genomic DNA into two daughter cells during cell division. Although more than 100 years …

This review is based on a thorough description of the structure and sequence organization
of tandemly organized repetitive DNA sequence families in the human genome; it is aimed …

Studies of 3D chromatin organization have suggested that chromosomes are hierarchically
organized into large compartments composed of smaller domains called topologically …