Blood-brain barrier dysfunction and recovery after ischemic stroke

X Jiang, AV Andjelkovic, L Zhu, T Yang… - Progress in …, 2018 - Elsevier
The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

Blood–brain barrier pathophysiology in traumatic brain injury

A Chodobski, BJ Zink… - Translational stroke …, 2011 - Springer
The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial
cells, but its normal function also depends on paracrine interactions between the brain …

Blood-brain barrier protection as a therapeutic strategy for acute ischemic stroke

AE Sifat, B Vaidya, TJ Abbruscato - The AAPS Journal, 2017 - Springer
The blood-brain barrier (BBB) is a vital component of the neurovascular unit (NVU)
containing tight junctional (TJ) proteins and different ion and nutrient transporters which …

Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

C Yang, KE Hawkins, S Doré… - American Journal of …, 2019 - journals.physiology.org
As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and recovery

S Bernardo-Castro, JA Sousa, A Brás, C Cecília… - Frontiers in …, 2020 - frontiersin.org
The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …

Blood− brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury

R Prakash, ST Carmichael - Current opinion in neurology, 2015 - journals.lww.com
Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …

[HTML][HTML] The blood brain barrier in cerebral ischemic injury–Disruption and repair

W Zhang, L Zhu, C An, R Wang, L Yang, W Yu, P Li… - Brain …, 2020 - Elsevier
With the emergence of novel technologies and ground breaking concepts in BBB basic
research in the past decades, the researchers' attention on the critical role of blood brain …

[HTML][HTML] Blood–brain barrier pathophysiology following traumatic brain injury

L Price, C Wilson, G Grant - Translational research in traumatic …, 2016 - ncbi.nlm.nih.gov
In the past, the neuron has been the focal point of brain injury research. However, in recent
years, the pathophysiology of the blood-brain barrier (BBB) has become increasingly more …

Blood–brain barrier breakdown in acute and chronic cerebrovascular disease

Y Yang, GA Rosenberg - Stroke, 2011 - Am Heart Assoc
Disruptions of the blood–brain barrier (BBB) and edema formation both play key roles in the
development of neurological dysfunction in acute and chronic cerebral ischemia. Animal …

Crosstalk between Inflammation and the BBB in Stroke

Y Huang, S Chen, Y Luo, Z Han - Current neuropharmacology, 2020 - ingentaconnect.com
The blood-brain barrier (BBB), which is located at the interface between the central nervous
system (CNS) and the circulatory system, is instrumental in establishing and maintaining the …