The notion that fibrinogen is strongly, consistently, and independently related to
cardiovascular risk has been widely accepted. The evidence is based on numerous …

The hypothesis that fibrinogen is closely related to cardiovascular risk has been
strengthened through the results of various lines of research, which this review will aim to …

Mounting data support a causal connection between high-normal fibrinogen levels and
atherosclerotic cardiovascular disease. There is clearly a thrombogenic component to …

Results from prevalence, case-control, angiographic and echocardiographic investigations
incriminate elevated fibrinogen levels as a strong independent risk factor for the occurrence …

Fibrinogen plays a key role in platelet aggregation, the final step of the coagulation cascade,
ie the formation of fibrin, and it is a major determinant of plasma viscosity and erythrocyte …

Several epidemiological studies have produced longitudinal data identifying fibrinogen as a
major cardiovascular risk factor. Cross-sectional results show strong associations between …

Results of epidemiological studies have indicated that fibrinogen is an important primary
cardiovascular risk factor. The role of fibrinogen as a predictor of mortality in coronary heart …

Fibrinogen contributes to both pathological and clinical manifestations of ischaemic heart
disease (IHD). Several cross-sectional angiographic studies have shown correlations …

Ischaemic heart disease and stroke are the major causes of death in the Western world.
Established risk factors such as smoking, hypertension and hypercholesterolemia explain …

An elevated plasma fibrinogen level is associated with increased frequency of coronary
heart disease and stoke. Although fibrinogen is also associated with other well-known risk …