Several methods are available for non-invasive imaging of gene delivery and transgene
expression, including magnetic resonance imaging (MRI), single photon emission …

Gene therapy is reaching a stage where some clinical benefits have been demonstrated on
patients involved in phase I/II clinical trials. However, in many cases, the clinical benefit is …

Recent progress in the development of noninvasive imaging technologies should allow
molecular imaging to play a major role in the field of gene therapy. These tools have recently …

Recent progress in scientific and clinical research has made gene therapy a promising
option for efficient and targeted treatment of several inherited and acquired disorders. One of …

Gene therapy of cancer has been one of the most exciting and elusive areas of scientific and
clinical research in the past decade. One of the most critical issues for ensuring success of …

Gene therapy is increasingly used experimentally and clinically to replace defective genes
and/or impart new functions to cells and tissues. With the recent advances in vector design …

Gene therapy is a very attractive strategy in experimental cancer therapy. Ideally, the
approach aims to deliver therapeutic genes selectively to cancer cells. However, progress in …

Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …

Recent progress in the development of high-resolution imaging techniques and reporter
probes is expected to revolutionize molecular imaging research in animal models of human …

With the ability to readily engineer genes, create knock-in and knock-out models of human
disease, and replace and insert genes in clinical trials of gene therapy, it has become clear …