miRNAs as potential game-changers in melanoma: a comprehensive review

GM Abd-Allah, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …

[PDF][PDF] MicroRNA signature in melanoma: biomarkers and therapeutic targets

S Ghafouri-Fard, M Gholipour, M Taheri - Frontiers in Oncology, 2021 - frontiersin.org
Melanoma is the utmost fatal kind of skin neoplasms. Molecular changes occurring during
the pathogenic processes of initiation and progression of melanoma are diverse and include …

[HTML][HTML] MicroRNAs as potential diagnostic and prognostic biomarkers in melanoma

H Mirzaei, S Gholamin, S Shahidsales… - European journal of …, 2016 - Elsevier
Melanoma is a life-threatening malignancy with poor prognosis and a relatively high burden
of mortality in advanced stages. The efficacy of current available therapeutic strategies is …

[HTML][HTML] The miRNAs role in melanoma and in its resistance to therapy

F Varrone, E Caputo - International Journal of Molecular Sciences, 2020 - mdpi.com
Melanoma is the less common but the most malignant skin cancer. Since the survival rate of
melanoma metastasis is about 10–15%, many different studies have been carried out in …

MicroRNAs in melanoma biology

M Kunz - … concepts, bioinformatics and systems biology tools, 2013 - Springer
Malignant melanoma is a highly aggressive tumour with increasing incidence and poor
prognosis in the metastatic stage. In recent years, a substantial number of reports on …

MicroRNAs in cutaneous melanoma: Role as diagnostic and prognostic biomarkers

CL Ross, S Kaushik… - Journal of cellular …, 2018 - Wiley Online Library
Melanoma is the leading cause of skin cancer deaths in the United States, and its incidence
has been rising steadily for the past 30 years (Aftab, Dinger, & Perera, 2014). A more …

[HTML][HTML] MicroRNA expression profiles associated with mutational status and survival in malignant melanoma

S Caramuta, S Egyházi, M Rodolfo, D Witten… - Journal of Investigative …, 2010 - Elsevier
Malignant cutaneous melanoma is a highly aggressive form of skin cancer. Despite
improvements in early melanoma diagnosis, the 5-year survival rate remains low in …

MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy

MF Segura, HS Greenwald, D Hanniford… - …, 2012 - academic.oup.com
Melanoma incidence and associated mortality continue to increase worldwide. The lack of
treatments with durable responses for stage IV melanoma may be due, at least in part, to an …

[HTML][HTML] Role of miRNAs in the progression of malignant melanoma

DW Mueller, AK Bosserhoff - British journal of cancer, 2009 - nature.com
Abstract Analysis of microRNA (miRNA) biogenesis and function is an area of research that
started only recently but has subsequently accelerated tremendously. This is because of the …

[HTML][HTML] Role of miRNAs in melanoma metastasis

A Gajos-Michniewicz, M Czyz - Cancers, 2019 - mdpi.com
Tumour metastasis is a multistep process. Melanoma is a highly aggressive cancer and
metastasis accounts for the majority of patient deaths. microRNAs (miRNAs) are non-coding …