Spiders use structural conversion of globular amyloidogenic domains to make strong silk fibers

X Qi, H Wang, K Wang, Y Wang… - Advanced Functional …, 2024 - Wiley Online Library
Spider silk—an environmentally friendly protein‐based material—is widely recognized for its
extraordinary mechanical properties. Biomimetic spider silk‐like fibers made from …

Engineered spider silk proteins for biomimetic spinning of fibers with toughness equal to dragline silks

T Arndt, G Greco, B Schmuck, J Bunz… - Advanced functional …, 2022 - Wiley Online Library
Spider silk is the toughest fiber found in nature, and bulk production of artificial spider silk
that matches its mechanical properties remains elusive. Development of miniature spider …

Properties of biomimetic artificial spider silk fibers tuned by PostSpin bath incubation

G Greco, J Francis, T Arndt, B Schmuck, F G. Bäcklund… - Molecules, 2020 - mdpi.com
Efficient production of artificial spider silk fibers with properties that match its natural
counterpart has still not been achieved. Recently, a biomimetic process for spinning …

Recombinant silk fiber properties correlate to prefibrillar self‐assembly

L Xu, N Weatherbee‐Martin, XQ Liu, JK Rainey - Small, 2019 - Wiley Online Library
Spider silks are desirable materials with mechanical properties superior to most synthetic
materials coupled with biodegradability and biocompatibility. In order to replicate natural silk …

Doing what spiders cannot—A road map to supreme artificial silk fibers

J Johansson, A Rising - ACS nano, 2021 - ACS Publications
Fabricating artificial spider silk fibers in bulk scale has been a major goal in materials
science for centuries. Two main routes have emerged for making such fibers. One method …

Critical role of minor eggcase silk component in promoting spidroin chain alignment and strong fiber formation

T Fan, R Qin, Y Zhang, J Wang… - Proceedings of the …, 2021 - National Acad Sciences
Natural spider silk with extraordinary mechanical properties is typically spun from more than
one type of spidroin. Although the main components of various spider silks have been …

Engineered disulfides improve mechanical properties of recombinant spider silk

S Grip, J Johansson, M Hedhammar - Protein Science, 2009 - Wiley Online Library
Nature's high‐performance polymer, spider silk, is composed of specific proteins, spidroins,
which form solid fibers. So far, fibers made from recombinant spidroins have failed in …

Engineered large spider eggcase silk protein for strong artificial fibers

Z Lin, Q Deng, XY Liu, D Yang - Advanced materials, 2013 - Wiley Online Library
Spiders employ different combinations of silk proteins to produce up to seven types of silks
with distinct mechanical properties for various purposes, ranging from prey capture to …

Recombinant spidroins fully replicate primary mechanical properties of natural spider silk

CH Bowen, B Dai, CJ Sargent, W Bai… - …, 2018 - ACS Publications
Despite significant efforts to engineer their heterologous production, recombinant spider silk
proteins (spidroins) have yet to replicate the unparalleled combination of high strength and …

Spider silk protein forms amyloid‐like nanofibrils through a non‐nucleation‐dependent polymerization mechanism

X Qi, Y Wang, H Yu, R Liu, A Leppert, Z Zheng… - Small, 2023 - Wiley Online Library
Amyloid fibrils—nanoscale fibrillar aggregates with high levels of order—are pathogenic in
some today incurable human diseases; however, there are also many physiologically …