An overview on display systems (phage, bacterial, and yeast display) for production of anticancer antibodies; advantages and disadvantages
Antibodies as ideal therapeutic and diagnostic molecules are among the top-selling drugs
providing considerable efficacy in disease treatment, especially in cancer therapy …
providing considerable efficacy in disease treatment, especially in cancer therapy …
[HTML][HTML] In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery properties
AS André, I Moutinho, JNR Dias… - Frontiers in …, 2022 - frontiersin.org
The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
Phage display antibody libraries: A robust approach for generation of recombinant human monoclonal antibodies
R Kumar, HA Parray, T Shrivastava, S Sinha… - International journal of …, 2019 - Elsevier
Monoclonal antibodies (mAbs) and their derivatives have achieved remarkable success as
medicine, targeting both diagnostic and therapeutic applications associated with …
medicine, targeting both diagnostic and therapeutic applications associated with …
Phage display for the generation of antibodies for proteome research, diagnostics and therapy
T Schirrmann, T Meyer, M Schütte, A Frenzel, M Hust - Molecules, 2011 - mdpi.com
Twenty years after its development, antibody phage display using filamentous
bacteriophage represents the most successful in vitro antibody selection technology. Initially …
bacteriophage represents the most successful in vitro antibody selection technology. Initially …
Considerations on antibody-phage display methodology
U Conrad, J Scheller - Combinatorial chemistry & high …, 2005 - ingentaconnect.com
For almost 15 years phage display is being used for the selection of specific antigen-binders
from artificial libraries of single chain antibodies. Filamentous phages have been developed …
from artificial libraries of single chain antibodies. Filamentous phages have been developed …
Phage display libraries for antibody therapeutic discovery and development
Phage display technology has played a key role in the remarkable progress of discovering
and optimizing antibodies for diverse applications, particularly antibody-based drugs. This …
and optimizing antibodies for diverse applications, particularly antibody-based drugs. This …
Phage display antibodies for diagnostic applications
With major developments in molecular biology, numerous display technologies have been
successfully introduced for recombinant antibody production. Even so, phage display still …
successfully introduced for recombinant antibody production. Even so, phage display still …
Antibody discovery: phage display
T Kretzschmar, T Von Rüden - Current opinion in biotechnology, 2002 - Elsevier
Phage display has proven to be a robust and convenient technology for the selection of high-
quality human antibodies from diverse libraries. Besides enabling the identification of …
quality human antibodies from diverse libraries. Besides enabling the identification of …
Biotechnological applications of phage and cell display
I Benhar - Biotechnology advances, 2001 - Elsevier
In recent years, the use of surface-display vectors for displaying polypeptides on the surface
of bacteriophage and bacteria, combined with in vitro selection technologies, has …
of bacteriophage and bacteria, combined with in vitro selection technologies, has …
[HTML][HTML] Phage display derived monoclonal antibodies: from bench to bedside
MA Alfaleh, HO Alsaab, AB Mahmoud… - Frontiers in …, 2020 - frontiersin.org
Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …
biopharmaceutical products, and they continue to dominate the universe of …
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