Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone
JL Coburn, TB Cole, KT Dao, LG Costa - Archives of toxicology, 2018 - Springer
Adult neurogenesis is the process by which neural stem cells give rise to new functional
neurons in specific regions of the adult brain, a process that occurs throughout life …
neurons in specific regions of the adult brain, a process that occurs throughout life …
[HTML][HTML] Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina …
TB Cole, YC Chang, K Dao, R Daza, R Hevner… - Journal of …, 2020 - Springer
Background Exposure to traffic-related air pollution (TRAP) during development and/or in
adulthood has been associated in many human studies with both neurodevelopmental and …
adulthood has been associated in many human studies with both neurodevelopmental and …
[HTML][HTML] Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease
S Levesque, MJ Surace, J McDonald… - Journal of …, 2011 - Springer
Background Increasing evidence links diverse forms of air pollution to neuroinflammation
and neuropathology in both human and animal models, but the effects of long-term …
and neuropathology in both human and animal models, but the effects of long-term …
Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain
TB Cole, J Coburn, K Dao, P Roqué, YC Chang… - Toxicology, 2016 - Elsevier
In addition to increased morbidity and mortality caused by respiratory and cardiovascular
diseases, air pollution may also contribute to central nervous system (CNS) diseases. Traffic …
diseases, air pollution may also contribute to central nervous system (CNS) diseases. Traffic …
Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity
S Levesque, T Taetzsch, ME Lull… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Air pollution is linked to central nervous system disease, but the mechanisms
responsible are poorly understood. Objectives: Here, we sought to address the brain-region …
responsible are poorly understood. Objectives: Here, we sought to address the brain-region …
Atypical microglial response to biodiesel exhaust in healthy and hypertensive rats
CL Mumaw, M Surace, S Levesque, UP Kodavanti… - Neurotoxicology, 2017 - Elsevier
Accumulating evidence suggests a deleterious role for urban air pollution in central nervous
system (CNS) diseases and neurodevelopmental disorders. Microglia, the resident innate …
system (CNS) diseases and neurodevelopmental disorders. Microglia, the resident innate …
The effect of diesel exhaust exposure on blood–brain barrier integrity and function in a murine model
S Heidari Nejad, R Takechi, BJ Mullins… - Journal of Applied …, 2015 - Wiley Online Library
Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with
vascular‐based disorders. To investigate the effect of DE on blood–brain barrier (BBB) …
vascular‐based disorders. To investigate the effect of DE on blood–brain barrier (BBB) …
Tobacco smoke diminishes neurogenesis and promotes gliogenesis in the dentate gyrus of adolescent rats
AW Bruijnzeel, RM Bauzo, V Munikoti, GB Rodrick… - Brain research, 2011 - Elsevier
Brain disorders and environmental factors can affect neurogenesis and gliogenesis in the
hippocampus. These studies investigated the effects of chronic exposure to tobacco smoke …
hippocampus. These studies investigated the effects of chronic exposure to tobacco smoke …
[HTML][HTML] Gestational exposure to air pollution alters cortical volume, microglial morphology, and microglia-neuron interactions in a sex-specific manner
JL Bolton, S Marinero, T Hassanzadeh… - Frontiers in synaptic …, 2017 - frontiersin.org
Microglia are the resident immune cells of the brain, important for normal neural
development in addition to host defense in response to inflammatory stimuli. Air pollution is …
development in addition to host defense in response to inflammatory stimuli. Air pollution is …
In utero exposure of mice to diesel exhaust particles affects spatial learning and memory with reduced N-methyl-d-aspartate receptor expression in the hippocampus …
S Yokota, A Sato, M Umezawa, S Oshio, K Takeda - Neurotoxicology, 2015 - Elsevier
Diesel exhaust consists of diesel exhaust particles (DEPs) and gaseous compounds.
Previous studies reported that in utero exposure to diesel exhaust affects the central nervous …
Previous studies reported that in utero exposure to diesel exhaust affects the central nervous …
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