Oral delivery of anticancer drugs III: formulation using drug delivery systems

S Mazzaferro, K Bouchemal, G Ponchel - Drug discovery today, 2013 - Elsevier
In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst
into challenging innovations enabling real progresses to achieve oral delivery of anticancer …

Pharmaceutical nanotechnology for oral delivery of anticancer drugs

L Mei, Z Zhang, L Zhao, L Huang, XL Yang… - Advanced drug delivery …, 2013 - Elsevier
Oral chemotherapy is an important topic in the 21st century medicine, which may radically
change the current regimen of chemotherapy and greatly improve the quality of life of the …

Drug delivery systems: entering the mainstream

TM Allen, PR Cullis - Science, 2004 - science.org
Drug delivery systems (DDS) such as lipid-or polymer-based nanoparticles can be designed
to improve the pharmacological and therapeutic properties of drugs administered …

Challenges and opportunities in the delivery of cancer therapeutics: update on recent progress

M Lorscheider, A Gaudin, J Nakhlé, KL Veiman… - Therapeutic …, 2021 - Taylor & Francis
Global cancer prevalence has continuously increased in the last decades despite
substantial progress achieved for patient care. Cancer is no longer recognized as a singular …

Advances in oral delivery of anti-cancer prodrugs

AK Jain, S Jain - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Most anticancer drugs have poor aqueous solubility and low permeability
across the gastrointestinal tract. Furthermore, extensive efflux by P-glycoproteins (P-gp) in …

Nanotherapeutics in oral and parenteral drug delivery: Key learnings and future outlooks as we think small

P Tyagi, JA Subramony - Journal of Controlled Release, 2018 - Elsevier
Nanotechnology ushered the field of medicine in to a new era. Miniaturization, increased
surface area, and the unique physicochemical properties in the nano dimension were …

Trends on polymer-and lipid-based nanostructures for parenteral drug delivery to tumors

E Ajorlou, AY Khosroushahi - Cancer chemotherapy and pharmacology, 2017 - Springer
Purpose The dawn of the state-of-the-art methods of cancer treatments, nano-based delivery
systems, has dispensed with the mainstream chemotherapy for being inadequate in yielding …

Current trends of targeted drug delivery for oral cancer therapy

M Zhang, J Liang, Y Yang, H Liang, H Jia… - … in bioengineering and …, 2020 - frontiersin.org
Oral cancer is an aggressive tumor that invades the local tissue and can cause metastasis
and high mortality. Conventional treatment strategies, eg, surgery, chemotherapy, and …

Anticancer drug delivery: an update on clinically applied nanotherapeutics

S Marchal, AE Hor, M Millard, V Gillon, L Bezdetnaya - Drugs, 2015 - Springer
The development of chemotherapy using conventional anticancer drugs has been hindered
due to several drawbacks related to their poor water solubility and poor pharmacokinetics …

[HTML][HTML] Recent advances in long-acting drug delivery systems for anticancer drug

C Pacheco, A Baiao, T Ding, W Cui… - Advanced Drug Delivery …, 2023 - Elsevier
The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …