Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders
P Auvinen, J Vehviläinen, H Marjonen, V Modhukur… - BMC medicine, 2022 - Springer
Background Prenatal alcohol exposure (PAE) affects embryonic development, causing a
variable fetal alcohol spectrum disorder (FASD) phenotype with neuronal disorders and birth …
variable fetal alcohol spectrum disorder (FASD) phenotype with neuronal disorders and birth …
Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation
Alcohol exposure during development can cause variable neurofacial deficit and growth
retardation known as fetal alcohol spectrum disorders (FASD). The mechanism underlying …
retardation known as fetal alcohol spectrum disorders (FASD). The mechanism underlying …
DNA methylation signature of human fetal alcohol spectrum disorder
E Portales-Casamar, AA Lussier, MJ Jones… - Epigenetics & …, 2016 - Springer
Background Prenatal alcohol exposure is the leading preventable cause of behavioral and
cognitive deficits, which may affect between 2 and 5% of children in North America. While …
cognitive deficits, which may affect between 2 and 5% of children in North America. While …
Associative DNA methylation changes in children with prenatal alcohol exposure
Aim: Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD).
Previously, we assessed PAE in brain tissue from mouse models, however whether these …
Previously, we assessed PAE in brain tissue from mouse models, however whether these …
Prenatal alcohol exposure: profiling developmental DNA methylation patterns in central and peripheral tissues
Background: Prenatal alcohol exposure (PAE) can alter the development of neurobiological
systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits …
systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits …
Expression quantitative trait methylation analysis identifies whole blood molecular footprint in fetal alcohol spectrum disorder (FASD)
IM Krzyzewska, P Lauffer, AN Mul… - International journal of …, 2023 - mdpi.com
Fetal alcohol spectrum disorder (FASD) encompasses neurodevelopmental disabilities and
physical birth defects associated with prenatal alcohol exposure. Previously, we attempted …
physical birth defects associated with prenatal alcohol exposure. Previously, we attempted …
DNA methylation as a predictor of fetal alcohol spectrum disorder
AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …
Meta‐Analysis of Gene Expression Patterns in Animal Models of Prenatal Alcohol Exposure Suggests Role for Protein Synthesis Inhibition and Chromatin Remodeling
S Rogic, A Wong, P Pavlidis - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) can result in an array of morphological,
behavioral, and neurobiological deficits that can range in their severity. Despite extensive …
behavioral, and neurobiological deficits that can range in their severity. Despite extensive …
Cell type-specific changes in Wnt signaling and neuronal differentiation in the developing mouse cortex after prenatal alcohol exposure during neurogenesis
Fetal Alcohol Spectrum Disorder (FASD) encompasses an array of effects of prenatal
alcohol exposure (PAE), including physical abnormalities and cognitive and behavioral …
alcohol exposure (PAE), including physical abnormalities and cognitive and behavioral …
Pre-implantation alcohol exposure and developmental programming of FASD: an epigenetic perspective
LM Legault, V Bertrand-Lehouillier… - Biochemistry and cell …, 2018 - cdnsciencepub.com
Exposure to alcohol during in-utero development can permanently change the
developmental programming of physiological responses, thereby increasing the risk of …
developmental programming of physiological responses, thereby increasing the risk of …