Adenosine receptors and the central nervous system
AM Sebastiao, JA Ribeiro - Adenosine receptors in health and disease, 2009 - Springer
The adenosine receptors (ARs) in the nervous system act as a kind of “go-between” to
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …
Tuning and fine-tuning of synapses with adenosine
AM Sebastião, JA Ribeiro - Current neuropharmacology, 2009 - ingentaconnect.com
The 'omnipresence'of adenosine in all nervous system cells (neurons and glia) together with
the intensive release of adenosine following insults, makes adenosine as a sort of …
the intensive release of adenosine following insults, makes adenosine as a sort of …
Adenosine receptors in the nervous system: pathophysiological implications
JA Ribeiro, AM Sebastiao, A De Mendonça - Progress in neurobiology, 2002 - Elsevier
Adenosine is a ubiquitous homeostatic substance released from most cells, including
neurones and glia. Once in the extracellular space, adenosine modifies cell functioning by …
neurones and glia. Once in the extracellular space, adenosine modifies cell functioning by …
Modulation and metamodulation of synapses by adenosine
JA Ribeiro, AM Sebastião - Acta physiologica, 2010 - Wiley Online Library
The presence of adenosine in all nervous system cells (neurones and glia) together with its
intensive release following insults makes adenosine as a sort of 'regulator'of synaptic …
intensive release following insults makes adenosine as a sort of 'regulator'of synaptic …
[HTML][HTML] Adenosine receptors and brain diseases: neuroprotection and neurodegeneration
Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors
RA Cunha - Neurochemistry international, 2001 - Elsevier
Adenosine exerts two parallel modulatory roles in the CNS, acting as a homeostatic
modulator and also as a neuromodulator at the synaptic level. We will present evidence to …
modulator and also as a neuromodulator at the synaptic level. We will present evidence to …
Adenosine receptor neurobiology: overview
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the
body as a metabolic intermediary. In the brain, adenosine functions as an important …
body as a metabolic intermediary. In the brain, adenosine functions as an important …
Adenosine and its receptors: multiple modulatory functions and potential therapeutic targets for neurologic disease
EE Benarroch - Neurology, 2008 - AAN Enterprises
Adenosine is a ubiquitous chemical messenger that modulates cellular activity in both the
CNS and peripheral organs. 1-5 Adenosine levels in the brain extracellular space increase …
CNS and peripheral organs. 1-5 Adenosine levels in the brain extracellular space increase …
Adenosine and related drugs in brain diseases: present and future in clinical trials
LV Lopes, AM Sebastiao… - Current topics in …, 2011 - ingentaconnect.com
Adenosine is a naturally occurring nucleoside present ubiquitously throughout the body as a
metabolic intermediate. Besides its metabolic role within the cells, adenosine is released …
metabolic intermediate. Besides its metabolic role within the cells, adenosine is released …
Adenosine receptors and neurological disease: neuroprotection and neurodegeneration
Adenosine receptors modulate neuronal and synaptic function in a range of ways that may
make them relevant to the occurrence, development and treatment of brain ischemic …
make them relevant to the occurrence, development and treatment of brain ischemic …