B Lymphocytes and Cancer: A Love–Hate Relationship: Trends in Cancer Skip to Main Content
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Whereas T cells have been considered the major immune cells of the tumor
microenvironment able to induce tumor regression and control cancer clinical outcome, a …

There is increasing evidence supporting a role for B cells in tumor immunology.
Paraneoplastic syndromes occurring before a cancer diagnosis have pointed to the potential …

The essential role played by T cells in anticancer immunity is widely accepted. The
immunosuppressive functions of regulatory T cells are central for tumor progression and …

Tumor-infiltrating B cells complement T cell-mediated antitumor immunity. A panel of experts
share their views on the complexity of B cells within the tumor microenvironment, the variety …

The opposing roles of innate and adaptive immune cells in suppressing or supporting
cancer initiation, progression, metastasis and response to therapy has been long debated …

B cells play a critical role in adaptive immune responses mainly due to antigen presentation
and antibody production. Studies about the tumor-infiltrating immune cells so far …

B cells infiltrating into solid tumors are poorly investigated despite their described positive
prognostic value. Whether this antitumor potential comes from either the antigen …

B regulatory cells are a newly described subpopulation of B cells that appear to play
important roles in autoimmunity and more recently, in cancer. In this review we summarize …

B cells have recently been appreciated as paracrine mediators of solid tumor development.
Their ability to influence various hallmarks of cancer development, aside from antigen …