[HTML][HTML] First passage time in post-transcriptional regulation by multiple small RNAs
The post-transcriptional regulation of a protein by multiple small RNA molecules has been
formulated as a stochastic process. An approximate solution of the master equation shows …
formulated as a stochastic process. An approximate solution of the master equation shows …
Timing effciency in small-rna-regulated post-transcriptional processes
Gene regulation in a cellular environment is a stochastic phenomenon leading to a large
variability in mRNAs and protein numbers that are often produced in bursts. The regulation …
variability in mRNAs and protein numbers that are often produced in bursts. The regulation …
Intrinsic noise in post-transcriptional gene regulation by small non-coding RNA
Y Jia, W Liu, A Li, L Yang, X Zhan - Biophysical Chemistry, 2009 - Elsevier
Small non-coding RNA (sRNA) plays very important role in the post transcriptional
regulation in various organisms. In complex regulatory networks, highly significant relative …
regulation in various organisms. In complex regulatory networks, highly significant relative …
[HTML][HTML] Stochastic modeling of gene regulation by noncoding small rnas in the strong interaction limit
Noncoding small RNAs (sRNAs) are known to play a key role in regulating diverse cellular
processes, and their dysregulation is linked to various diseases such as cancer. Such …
processes, and their dysregulation is linked to various diseases such as cancer. Such …
First-passage time statistics of stochastic transcription process for time-dependent reaction rates
Transcription in gene expression is an intrinsically noisy process which involves production
and degradation of mRNAs. An important quantity to describe this stochastic process is the …
and degradation of mRNAs. An important quantity to describe this stochastic process is the …
Effects of the promoter open complex formation on gene expression dynamics
AS Ribeiro, A Häkkinen, H Mannerström… - Physical Review E …, 2010 - APS
Little is known about the biological mechanisms that shape the distribution of intervals
between the completion of RNA molecules (T p RNA), and thus transcriptional noise. We …
between the completion of RNA molecules (T p RNA), and thus transcriptional noise. We …
Stochastic single-gene autoregulation
A detailed stochastic model of single-gene autoregulation is established and its solutions
are explored when mRNA dynamics is fast compared with protein dynamics and in the …
are explored when mRNA dynamics is fast compared with protein dynamics and in the …
Frequency modulation of stochastic gene expression bursts by strongly interacting small RNAs
The sporadic nature of gene expression at the single-cell level—long periods of inactivity
punctuated by bursts of mRNA or protein production—plays a critical role in diverse cellular …
punctuated by bursts of mRNA or protein production—plays a critical role in diverse cellular …
Synergistic effect of auto-activation and small RNA regulation on gene expression
X Li-Ping, M Yu-Qiang, T Lei-Han - Chinese Physics Letters, 2010 - iopscience.iop.org
Auto-activation and small ribonucleic acid (RNA)-mediated regulation are two important
mechanisms in controlling gene expression. We study the synergistic effect of these two …
mechanisms in controlling gene expression. We study the synergistic effect of these two …
[HTML][HTML] Small RNAs establish delays and temporal thresholds in gene expression
Noncoding RNAs are crucial regulators of gene expression in prokaryotes and eukaryotes,
but how they affect the dynamics of transcriptional networks remains poorly understood. We …
but how they affect the dynamics of transcriptional networks remains poorly understood. We …