The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment

A Takahashi - Physiological Reports, 2021 - Wiley Online Library
Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the
administration of carnitine, but this is not effective in every patient. Alkalosis is a key …

Effects of L-carnitine on dialysis-related hypotension and muscle cramps: a meta-analysis

KE Lynch, HI Feldman, JA Berlin, J Flory… - American Journal of …, 2008 - Elsevier
BACKGROUND: l-Carnitine is an endogenous compound thought to be helpful in treating
patients with dialysis-related hypotension and muscle cramps; however, sufficient evidence …

Effects of L-carnitine supplementation on muscular symptoms in hemodialyzed patients

Y Sakurauchi, Y Matsumoto, T Shinzato, I Takai… - American journal of …, 1998 - ajkd.org
Various muscle symptoms are well recognized among patients on maintenance
hemodialysis. Carnitine deficiency may be an important factor of dialysis-associated muscle …

On the evolving nature of understanding dialysis-related disorders

G Eknoyan, JS Lindberg - American journal of kidney diseases, 2003 - ajkd.org
American Journal of Kidney Diseases, Vol 41, No 4, Suppl 4 (April), 2003: pp S1-S3 S1
failure, carnitine's role in modulating the ratio of free coenzyme A to esterified coenzyme A …

Effects of l-Carnitine Supplementation in Patients Receiving Hemodialysis or Peritoneal Dialysis

M Kuwasawa-Iwasaki, H Io, M Muto, S Ichikawa… - Nutrients, 2020 - mdpi.com
l-carnitine is an important factor in fatty acid metabolism, and carnitine deficiency is common
in dialysis patients. This study evaluated whether l-carnitine supplementation improved …

[引用][C] Carnitine metabolism and usage in chronic dialysis patients

PS Kurtin - Seminars in Dialysis, 1990 - Wiley Online Library
Chronic dialysis patients typically have numerous nutritional disturbances including
abnormal lipid metabolism. They may also experience adverse clinical consequences of …

Evaluation of the Effect of Intravenous L-Carnitine Therapy on Function, Structure and Fatty Acid Metabolism of Skeletal Muscle in Patients Receiving Chronic …

G Siami, ME Clinton, R Mrak, J Griffis, W Stone - Nephron, 1991 - karger.com
Chronic hemodialysis (HD) leads to significant losses of carnitine from plasma and muscle.
Because L-carnitine is important in the production of energy from fatty acid oxidation (FAO) …

Levocarnitine and dialysis: a review

B Schreiber - Nutrition in clinical practice, 2005 - Wiley Online Library
Among the various metabolic abnormalities documented in dialysis patients are
abnormalities related to the metabolism of fatty acids. Aberrant fatty‐acid metabolism has …

L-carnitine and haemodialysis: double blind study on muscle function and metabolism and peripheral nerve function

B Fagher, G Cederblad, M Eriksson… - … Journal of Clinical …, 1985 - Taylor & Francis
Twenty-eight haemodialysis patients were randomized to L-carnitine, 2 g iv three times a
week, and saline over a 6-week period. No obvious deficiency of carnitine was found in …

Carnitine and weakness in haemodialysis patients

ME Rogerson, PB Rylance, R Wilson… - Nephrology Dialysis …, 1989 - academic.oup.com
Weakness in haemodialysis patients has been attributed to several factors including
carnitine deficiency. Malnutrition, neuropathy, uraemic myopathy and parathyroid hormone …