Induced pluripotency has indeed revolutionized the field of pluripotent stem cell biology for
one and a half decades. However, embryonic stem cells (ESCs) have been finding their …

Abstract Derivation of induced Pluripotent Stem Cells (iPSCs) by reprogramming somatic
cells to a pluripotent state has revolutionized stem cell research. Ensuing this, various …

Induced pluripotent stem cells (iPSC s) are considered patient‐specific counterparts of
embryonic stem cells as they originate from somatic cells after forced expression of …

The induced pluripotent stem cells (iPSCs) are referred to as patient-specific equivalents of
embryonic stem cells for the reason that they originate from somatic cells once the forced …

The ground-breaking work of Yamanaka and Thomson showed that forced expression of
just four transcription factors can reprogram mouse and human somatic cells to pluripotency …

Human pluripotent stem cells hold great promise for basic research and regenerative
medicine due to their inherent property to propagate infinitely, while maintaining the …

Reprogramming shifts somatic cells toward a pluripotent state, resulting in cells that are
capable of producing any tissue type, which provides a unique system for regenerative …

Conversion of somatic cells into a pluripotent state is possible by the introduction of
reprogramming transcription factors (Oct4, Sox2, c-Myc, and Klf4) into somatic cells. Induced …

Induction of pluripotency and CRISPR/Cas9-mediated genome engineering have been two
of the most impactful biomedical innovations affecting the stem cell field in the past decade …

Induced pluripotent stem cells (iPSCs) have vast biomedical potential concerning disease
modeling, drug screening and discovery, cell therapy, tissue engineering, and …