The interleukin (IL)-23/IL-17 axis plays a central role in the pathogenesis of immune-
mediated diseases such as psoriasis, psoriatic arthritis, Crohn's disease, and uveitis …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Abstract Interleukin-6 (IL-6) is a key cytokine that is strongly up-regulated during infection
and inflammation. Featuring pleiotropic activity, IL-6 is responsible for the induction of …

Interleukin-17A (IL-17A) is elaborated by the T helper 17 (TH17) subset of TH cells and
exhibits potent proinflammatory properties in animal models of autoimmunity, including …

Abstract Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory
cytokine that has been shown to be involved in several forms of infectious and noninfectious …

Summary Interleukin-6 (IL-6) is a key cytokine featuring redundancy and pleiotropic activity.
It plays a central role in host defence against environmental stress such as infection and …

Interleukin-6 (IL-6) is a pleiotropic cytokine implicated in the pathogenesis of many immune-
mediated disorders including several types of non-infectious uveitis. These uveitic …

Purpose: To report the effect of adalimumab on serum cytokines in chronic refractory uveitis.
Methods: Prospective study on the effects of adalimumab on serum cytokine levels at …

Objectives. Human endogenous uveitis is one of the sight-threatening diseases associated
with variety of systemic disorders, such as Behcet's disease and sarcoidosis. Recently …

Background Uveitis consists of a spectrum of inflammatory disorders characterized by ocular
inflammation. The underlying pathophysiology consists of a complex interplay of various …