Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice
M Hoekstra, RJ van der Sluis, J Kuiper… - The Journal of nutritional …, 2012 - Elsevier
MicroRNAs modulate processes associated with cell cycle control and differentiation. Here
we explored the potential of microRNAs in the modulation of hepatic lipid metabolism and …
we explored the potential of microRNAs in the modulation of hepatic lipid metabolism and …
[HTML][HTML] Aberrant hepatic microRNA expression in nonalcoholic fatty liver disease
YY Feng, XQ Xu, CB Ji, CM Shi, XR Guo… - Cellular Physiology and …, 2014 - karger.com
Background/Aim: Emerging evidence suggests that microRNA (miRNA) mediated gene
regulation influences the maintenance of metabolic homeostasis, particularly the states of …
regulation influences the maintenance of metabolic homeostasis, particularly the states of …
[HTML][HTML] MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease
XC Wang, XR Zhan, XY Li, JJ Yu… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …
[HTML][HTML] MicroRNA-199a-3p attenuates hepatic lipogenesis by targeting Sp1
Y Cheng, L Huang, J Ping, T Chen… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Emerging studies have demonstrated that microRNAs (miRs) are profoundly involved in non-
alcoholic fatty liver disease (NAFLD) and related metabolic diseases. Previously, we …
alcoholic fatty liver disease (NAFLD) and related metabolic diseases. Previously, we …
Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia
AR Coffey, TL Smallwood, J Albright… - Physiological …, 2017 - journals.physiology.org
Chronically altered levels of circulating lipids, termed dyslipidemia, is a significant risk factor
for a number of metabolic and cardiovascular morbidities. MicroRNAs (miRNAs) have …
for a number of metabolic and cardiovascular morbidities. MicroRNAs (miRNAs) have …
Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons
GM Karere, JP Glenn, JL VandeBerg, LA Cox - BMC genomics, 2012 - Springer
Abstract Background Dysregulation of microRNA (miRNA) expression has been implicated
in molecular genetic events leading to the progression and development of atherosclerosis …
in molecular genetic events leading to the progression and development of atherosclerosis …
Concerted regulation of non-alcoholic fatty liver disease progression by microRNAs in apolipoprotein E-deficient mice
AR López-Pastor, J Infante-Menéndez… - Disease Models & …, 2021 - journals.biologists.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is constantly increasing, and
altered expression of microRNAs (miRNAs) fosters the development and progression of …
altered expression of microRNAs (miRNAs) fosters the development and progression of …
[PDF][PDF] Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice
MicroRNAs (miRs) are conserved, small (20‐25 nucleotide) noncoding RNAs that negatively
regulate expression of messenger RNAs (mRNAs) at the posttranscriptional level. Aberrant …
regulate expression of messenger RNAs (mRNAs) at the posttranscriptional level. Aberrant …
High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis
J Ahn, H Lee, CH Chung, T Ha - Biochemical and biophysical research …, 2011 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation and is
presently the most common chronic liver disease. However, the mechanisms underlying the …
presently the most common chronic liver disease. However, the mechanisms underlying the …
Liver microRNA-291b-3p promotes hepatic lipogenesis through negative regulation of adenosine 5′-monophosphate (AMP)-activated protein kinase α1
X Meng, J Guo, W Fang, L Dou, M Li, X Huang… - Journal of Biological …, 2016 - ASBMB
In a microarray study, we found that hepatic miR-291b-3p was significantly increased in
leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR …
leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR …