Poly(l‐Histidine)‐Mediated On‐Demand Therapeutic Delivery of Roughened Ceria Nanocages for Treatment of Chemical Eye Injury
Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …
bioavailability of conventional eye drops is critically important for efficient management of …
Biofunctionalization of nanoceria with sperminated hyaluronan enhances drug delivery performance for corneal alkali burn therapy
Corneal alkali burn (AB) injury is the most common sight-threatening injury that is highly
associated with oxidative stress, inflammation, apoptosis, angiogenesis, and cell deficiency …
associated with oxidative stress, inflammation, apoptosis, angiogenesis, and cell deficiency …
Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma …
Delivery of ophthalmic drugs to the interior parts of the eye for effective treatment of
glaucoma (ie, a chronic disease) remains a huge challenge because of the well-known …
glaucoma (ie, a chronic disease) remains a huge challenge because of the well-known …
[HTML][HTML] Harnessing the tunable cavity of nanoceria for enhancing Y-27632-mediated alleviation of ocular hypertension
Background: Y-27632 is a potent ophthalmic drug for the treatment of ocular hypertension, a
globally prevalent eye disease. However, the sustained delivery of Y-27632 by a therapeutic …
globally prevalent eye disease. However, the sustained delivery of Y-27632 by a therapeutic …
Amination-mediated nano eye-drops with enhanced corneal permeability and effective burst release for acute glaucoma treatment
The development of topical formulations with advanced functions to overcome the poor and
sluggish permeability/bioavailability of traditional eye drops into interior of the eye is …
sluggish permeability/bioavailability of traditional eye drops into interior of the eye is …
Unveiling the power of gabapentin-loaded nanoceria with multiple therapeutic capabilities for the treatment of dry eye disease
Dry eye (DE) disease, which is primarily linked to aqueous deficiency, is an escalating
health issue worldwide, mainly due to the widespread use of electronic devices. The major …
health issue worldwide, mainly due to the widespread use of electronic devices. The major …
Therapeutic hydrogel sheets programmed with multistage drug delivery for effective treatment of corneal abrasion
Corneal abrasion (CA) is a leading cause of inflammation, scar formation, and even loss of
vision in the eye if allowed to progress; however, current treatments remain constrained by …
vision in the eye if allowed to progress; however, current treatments remain constrained by …
Therapeutic contact lens for scavenging excessive reactive oxygen species on the ocular surface
Excessive reactive oxygen species (ROS) play a significant role in the pathogenesis of many
eye diseases. Controlling oxidative stress by reducing the amount of ROS is a potential …
eye diseases. Controlling oxidative stress by reducing the amount of ROS is a potential …
Advanced nanodelivery platforms for topical ophthalmic drug delivery
Highlights•Eye drops are applied at high frequency due to unique physio-anatomy of
corneal tissue.•Different types of nanodelivery platforms (medical devices) have been …
corneal tissue.•Different types of nanodelivery platforms (medical devices) have been …
Emerging trends in nanomedicine for improving ocular drug delivery: light-responsive nanoparticles, mesoporous silica nanoparticles, and contact lenses
FSC Rodrigues, A Campos, J Martins… - ACS Biomaterials …, 2020 - ACS Publications
Vision is the most dominant of our senses, and it is crucial in every stage of our lives. Ocular
diseases, regardless of whether they cause vision impairment or not, lead to personal and …
diseases, regardless of whether they cause vision impairment or not, lead to personal and …