Skin type, but neither race nor gender, influence epidermal permeability barrier function
JT Reed, R Ghadially, PM Elias - Archives of dermatology, 1995 - jamanetwork.com
Background and Design: Previous studies that compared transepidermal water loss in
subjects of different race and sex showed minimal differences in basal permeability barrier …
subjects of different race and sex showed minimal differences in basal permeability barrier …
Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models
JW Fluhr, KR Feingold, PM Elias - Experimental dermatology, 2006 - Wiley Online Library
Permeability barrier function is measured with instruments that assess transepidermal water
loss (TEWL), either with closed‐or open‐loop systems. Yet, the validity of TEWL as a …
loss (TEWL), either with closed‐or open‐loop systems. Yet, the validity of TEWL as a …
[HTML][HTML] Transepidermal water loss does not correlate with skin barrier function in vitro
RP Chilcott, CH Dalton, AJ Emmanuel, CE Allen… - Journal of Investigative …, 2002 - Elsevier
The purpose of this study was to investigate the relationship between transepidermal water
loss and skin permeability to tritiated water (3 H 2 O) and the lipophilic penetrant sulfur …
loss and skin permeability to tritiated water (3 H 2 O) and the lipophilic penetrant sulfur …
Influence of skin type, race, sex, and anatomic location on epidermal barrier function
R Darlenski, JW Fluhr - Clinics in dermatology, 2012 - Elsevier
The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma
components from the organism. Owing to its complex structure, the epidermal barrier with its …
components from the organism. Owing to its complex structure, the epidermal barrier with its …
[PDF][PDF] The epidermal permeability barrier: from the early days at Harvard to emerging concepts
PM Elias - The Journal of investigative dermatology, 2004 - core.ac.uk
Perhaps no tissue is so physically maligned by processing for light/electron microscopy as is
the stratum corneum (SC). To further complicate matters, no tissue of such critical …
the stratum corneum (SC). To further complicate matters, no tissue of such critical …
Defense against dermal exposures is only skin deep: significantly increased penetration through slightly damaged skin
JB Nielsen, F Nielsen, JA Sørensen - Archives of dermatological research, 2007 - Springer
The OECD guideline for studies on percutaneous penetration to be used in hazard and risk
evaluations prescribes experimental conditions with optimal barrier integrity of the skin …
evaluations prescribes experimental conditions with optimal barrier integrity of the skin …
Correlation of transepidermal water loss with skin barrier properties in vitro: comparison of three evaporimeters
R Elkeeb, X Hui, H Chan, L Tian… - Skin Research and …, 2010 - Wiley Online Library
Aim: This study investigates the relationship between transepidermal water loss (TEWL) and
skin permeability to tritiated water as a rapid assessment of the integrity of the barrier …
skin permeability to tritiated water as a rapid assessment of the integrity of the barrier …
Skin structure, function, and permeation
HAE Benson - … and Transdermal Drug delivery: Principles and …, 2012 - Wiley Online Library
The skin is the largest organ of the body, covering about 1.7 m 2 and comprising
approximately 10% of the total body mass of an average person. The primary function of the …
approximately 10% of the total body mass of an average person. The primary function of the …
Percutaneous transport in relation to stratum corneum structure and lipid composition
PM Elias, ER Cooper, A Korc, BE Brown - Journal of Investigative …, 1981 - Elsevier
Despite the acknowledged importance of the stratum corneum in limiting water loss and in
controlling skin corneum in limiting water loss and in controlling skin permeability, the basis …
controlling skin corneum in limiting water loss and in controlling skin permeability, the basis …
[HTML][HTML] Abrupt decreases in environmental humidity induce abnormalities in permeability barrier homeostasis
J Sato, M Denda, S Chang, PM Elias… - Journal of investigative …, 2002 - Elsevier
Previous reports demonstrated that long-term exposure to extremes in humidity influence
permeability barrier homeostasis. Here the effects of a sudden shift from a high humidity to a …
permeability barrier homeostasis. Here the effects of a sudden shift from a high humidity to a …