Background and Design: Previous studies that compared transepidermal water loss in
subjects of different race and sex showed minimal differences in basal permeability barrier …

Permeability barrier function is measured with instruments that assess transepidermal water
loss (TEWL), either with closed‐or open‐loop systems. Yet, the validity of TEWL as a …

The purpose of this study was to investigate the relationship between transepidermal water
loss and skin permeability to tritiated water (3 H 2 O) and the lipophilic penetrant sulfur …

The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma
components from the organism. Owing to its complex structure, the epidermal barrier with its …

Perhaps no tissue is so physically maligned by processing for light/electron microscopy as is
the stratum corneum (SC). To further complicate matters, no tissue of such critical …

The OECD guideline for studies on percutaneous penetration to be used in hazard and risk
evaluations prescribes experimental conditions with optimal barrier integrity of the skin …

Aim: This study investigates the relationship between transepidermal water loss (TEWL) and
skin permeability to tritiated water as a rapid assessment of the integrity of the barrier …

The skin is the largest organ of the body, covering about 1.7 m 2 and comprising
approximately 10% of the total body mass of an average person. The primary function of the …

Despite the acknowledged importance of the stratum corneum in limiting water loss and in
controlling skin corneum in limiting water loss and in controlling skin permeability, the basis …

Previous reports demonstrated that long-term exposure to extremes in humidity influence
permeability barrier homeostasis. Here the effects of a sudden shift from a high humidity to a …