Current research findings in humans and other mammalian and non-mammalian species
support the potent regulatory role of myostatin in the morphology and function of muscle as …

Myostatin is an endogenous, negative regulator of muscle growth determining both muscle
fiber number and size. The myostatin pathway is conserved across diverse species ranging …

Skeletal muscle is one of the leading frameworks of the musculo-skeletal system, which
works in synergy with the bones. Long skeletal muscles provide stability and mobility to the …

Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, can negatively
regulate the growth and development of skeletal muscle by autocrine or paracrine signaling …

Myostatin is a powerful negative regulator of skeletal muscle mass in mammalian species. It
plays a key role in skeletal muscle homeostasis and has now been well described since its …

Myostatin, a member of the transforming growth factor beta (TGF-β) superfamily, was first
described in 1997. Since then, myostatin has gained growing attention because of the …

Since its identification in 1997, myostatin has been considered as a novel and unique
negative regulator of muscle growth, as mstn−/− mice display a dramatic and widespread …

Myostatin was identified more than 20 years ago as a negative regulator of muscle mass in
mice and cattle. Since then, a wealth of studies have uncovered the potential involvement of …

Myostatin is a secreted growth and differentiation factor that belongs to the TGF‐β
superfamily. Myostatin is predominantly synthesized and expressed in skeletal muscle and …