Ellagic acid in Emblica officinalis exerts anti-diabetic activity through the action on β-cells of pancreas

N Fatima, RM Hafizur, A Hameed, S Ahmed… - European journal of …, 2017 - Springer
Purpose The present study was undertaken to explore the possible anti-diabetic mechanism
(s) of Emblica officinalis (EO) and its active constituent, ellagic acid (EA), in vitro and in vivo …

Randomized double‐blind clinical trial examining the Ellagic acid effects on glycemic status, insulin resistance, antioxidant, and inflammatory factors in patients with …

M Ghadimi, F Foroughi, S Hashemipour… - Phytotherapy …, 2021 - Wiley Online Library
Oxidative stress can worsen glycemic status. Considering the antioxidant properties of
Ellagic acid (EA), this study was designed to evaluate the effect of EA on glycemic indices …

Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin-induced type-2 diabetes mellitus (T2DM) rats

P Nain, V Saini, S Sharma, J Nain - Journal of Ethnopharmacology, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: In traditional Indian medicine, all parts of
Emblica officinalis Gaertn plant including the fruit, seed, leaves, root, bark and flowers are …

[HTML][HTML] Ellagic acid regulates hyperglycemic state through modulation of pancreatic IL-6 and TNF-α immunoexpression

MM Elbandrawy, O Sweef, D Elgamal… - Saudi Journal of …, 2022 - Elsevier
Abstract Background Type 2 diabetes (T2DM) is a chronic metabolic disorder. Although
therapeutic pharmaceutical agents continue to advance, herbal medicines are potential …

Anti-diabetic activity of Emblica officinalis in animal models

S Mehta, RK Singh, D Jaiswal, PK Rai… - Pharmaceutical …, 2009 - Taylor & Francis
The aqueous extract of Emblica officinalis Gaertn.(syn: Phyllanthus emblica
L.)(Euphorbiaceae) seeds was investigated for its anti-diabetic activity in animal models …

Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan‐induced diabetic rats

D Gao, Q Li, Y Li, Z Liu, Y Fan, Z Liu… - … Journal Devoted to …, 2009 - Wiley Online Library
The present study evaluated the antidiabetic and antioxidant effects of oleanolic acid (OA)
from Ligustrum lucidum Ait (LLA) in alloxan‐induced diabetic rats. OA in the alloxan …

Ellagic acid alleviates hepatic oxidative stress and insulin resistance in diabetic female rats

SA Polce, C Burke, LM França, B Kramer, AMA Paes… - Nutrients, 2018 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) affects more than 70% of patients with type 2
diabetes mellitus (T2DM) and has become one of the most common metabolic liver diseases …

Antidiabetic effect of oleanolic acid: a promising use of a traditional pharmacological agent

X Wang, YL Li, H Wu, JZ Liu, JX Hu… - Phytotherapy …, 2011 - Wiley Online Library
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia.
Although the clear mechanisms of DM and insulin resistance are still to be cleared, it has …

Hypoglycemic effects in alloxan-induced diabetic rats of the phenolic extract from mongolian oak cups enriched in ellagic acid, kaempferol and their derivatives

P Yin, Y Wang, L Yang, J Sui, Y Liu - Molecules, 2018 - mdpi.com
Our previous reports showed that crude extract prepared with 50% ethanol (ethanol crude
extract, ECE) from Mongolian oak cups possessed excellent in vitro antioxidant capacities …

Ellagic acid protects against diabetes-associated behavioral deficits in rats: Possible involved mechanisms

Y Farbood, M Rashno, S Ghaderi, SE Khoshnam… - Life sciences, 2019 - Elsevier
Aims Diabetes mellitus (DM), a chronic metabolic disease, is associated with behavioral
deficits. It has been suggested that ellagic acid (EA), a natural polyphenol compound, has …