Motor and non-motor symptoms, drugs, and their mode of action in Parkinson's disease (PD): a review

N Saini, N Singh, N Kaur, S Garg, M Kaur… - Medicinal Chemistry …, 2024 - Springer
Parkinson's disease is second most common neurodegenerative disorder neurological
illness that primarily affects patients in their later years of life. Specific neurons in the brain …

Novel and experimental therapeutics for the management of motor and non-motor Parkinsonian symptoms

I Ullah, X Wang, H Li - Neurological Sciences, 2024 - Springer
Background Both motor and non-motor symptoms of Parkinson's disease (PD) have a
substantial detrimental influence on the patient's quality of life. The most effective treatment …

A comprehensive review on management of Parkinson's disease, inclusive of drug discovery and pharmacological approaches

AN El-Shorbagi, S Chaudhary… - Journal of Applied …, 2020 - japsonline.com
Parkinson's disease (PD) is the second most prevailing neurodegenerative disorder and is
indicated by the degeneration of dopaminergic neurons within the substantia nigra; various …

Pre-clinical Aspects and Contemporary Treatments of Parkinson's Disease

P Chhabra, S Singla, S Choudhary… - CNS & Neurological …, 2024 - ingentaconnect.com
Background: After Alzheimer's disease, the second slot for the most common
neurodegenerative disease, is occupied by Parkinson's disease. The symptoms of …

New drugs in the future treatment of Parkinson's disease

R Djaldetti, E Melamed - Journal of Neurology, 2002 - Springer
During the last few decades, there has been a remarkable progress in our understanding of
the biology of Parkinson's disease (PD), which has been translated into the development of …

[PDF][PDF] Parkinson's Disease: Diagnosis, Therapeutics & Management

A Nagal, RK Singla - Webmed Central Pharmaceutical Sciences, 2012 - academia.edu
Parkinson disease is a chronic, progressive neurodegenerative movement which affects
about 1% of population over the age of 60. In Parkinson disease there is loss of …

Advances in anti-Parkinson′ s disease drugs and their related pharmacological targets

X Zhang, W Zhang, L DU, L Gao… - Journal of International …, 2016 - pesquisa.bvsalud.org
ABSTRACT Parkinson′ s disease (PD), the second neurodegenerative disease in the
world, is characterized by a combination of motor symptoms (rest tremor, bradykinesia …

Parkinson's disease: a review from pathophysiology to treatment

BLB Marino, LR de Souza, K Sousa… - Mini reviews in …, 2020 - ingentaconnect.com
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the
elderly population, with a higher prevalence in men, independent of race and social class; it …

Parkinson's disease: emerging pharmacotherapy

K Strecker, J Schwarz - Expert opinion on emerging drugs, 2008 - Taylor & Francis
Parkinson's disease (PD) is the second most common neurodegenerative disease. The
prevalence is increasing with age and averages approximately 0.3% in the entire …

Current pharmaceutical treatments and alternative therapies of Parkinson's disease

J Dong, Y Cui, S Li, W Le - Current neuropharmacology, 2016 - ingentaconnect.com
Over the decades, pharmaceutical treatments, particularly dopaminergic (DAergic) drugs
have been considered as the main therapy against motor symptoms of Parkinson's disease …