Saccharomyces boulardii, a yeast probiotic, inhibits gut motility through upregulating intestinal serotonin transporter and modulating gut microbiota

Y Gu, C Wang, X Qin, B Zhou, X Liu, T Liu, R Xie… - Pharmacological …, 2022 - Elsevier
Saccharomyces boulardii (Sb) is a widely used fungal probiotic in treating various digestive
diseases, including irritable bowel syndrome (IBS). However, the specific mechanisms of Sb …

Saccharomyces boulardii alleviates DSS-induced intestinal barrier dysfunction and inflammation in humanized mice

B Li, H Zhang, L Shi, R Li, Y Luo, Y Deng, S Li, R Li… - Food & Function, 2022 - pubs.rsc.org
Recent clinical studies have demonstrated a beneficial effect of Saccharomyces boulardii (S.
boulardii) in inflammatory bowel disease (IBD). However, the underlying mechanisms …

Lactobacillus rhamnosus GG supernatant upregulates serotonin transporter expression in intestinal epithelial cells and mice intestinal tissues

YM Wang, XZ Ge, WQ Wang, T Wang… - …, 2015 - Wiley Online Library
Background The role that probiotics play in relieving irritable bowel syndrome (IBS) has
been demonstrated; however, the mechanism by which IBS is affected remains unclear. In …

Dietary synbiotic ameliorates constipation through the modulation of gut microbiota and its metabolic function

Z Yang, S Ye, Z Xu, H Su, X Tian, B Han, B Shen… - Food Research …, 2021 - Elsevier
The purpose of this study is to investigate the mitigatory effect of a novel synbiotic (SBT) on
constipation from the perspective of gut microbiome and metabolome. Here, intake of SBT …

Selenium-enriched Bifidobacterium longum DD98 relieves irritable bowel syndrome induced by chronic unpredictable mild stress in mice

X Jin, Y Hu, T Lin, F Gao, Z Xu, X Hou, Y Yin, S Kan… - Food & Function, 2023 - pubs.rsc.org
Irritable bowel syndrome (IBS) is a functional intestinal disorder without clear pathological
mechanisms. Classical treatments for IBS are not always effective and are usually …

Saccharomyces boulardii administration changes gut microbiota and reduces hepatic steatosis, low-grade inflammation, and fat mass in obese and type 2 diabetic db …

A Everard, S Matamoros, L Geurts, NM Delzenne… - MBio, 2014 - Am Soc Microbiol
Growing evidence shows that gut microbes are key factors involved in the regulation of
energy homeostasis, metabolic inflammation, lipid metabolism, and glucose metabolism …

Probiotic yeast BR14 ameliorates DSS-induced colitis by restoring the gut barrier and adjusting the intestinal microbiota

Z Mu, Y Yang, Y Xia, F Wang, Y Sun, Y Yang, L Ai - Food & Function, 2021 - pubs.rsc.org
The probiotic Saccharomyces boulardii has been widely used in colitis treatment; however,
the beneficial effects of other yeast species are rarely studied. Saccharomyces cerevisiae …

Astragaloside IV alleviates mouse slow transit constipation by modulating gut microbiota profile and promoting butyric acid generation

Q He, C Han, L Huang, H Yang, J Hu… - Journal of Cellular …, 2020 - Wiley Online Library
Gut microbiota and short‐chain fatty acids (SCFAs) are associated with the development of
various human diseases. In this study, we examined the role of astragaloside IV in …

Bifidobacterium lactis TY-S01 Prevents Loperamide-Induced Constipation by Modulating Gut Microbiota and Its Metabolites in Mice

T Tang, J Wang, Y Jiang, X Zhu, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Probiotics have received widespread attention as a healthy ingredient. The preventive effect
of Bifidobacterium lactis TY-S01 on loperamide-induced constipation in mice was …

Saccharomyces boulardii CNCM I‐745 modulates the microbiota–gut–brain axis in a humanized mouse model of Irritable Bowel Syndrome

M Constante, G De Palma, J Lu, J Jury… - …, 2021 - Wiley Online Library
Background Gnotobiotic mice colonized with microbiota from patients with irritable bowel
syndrome (IBS) and comorbid anxiety (IBS+ A) display gut dysfunction and anxiety‐like …