Neutrophil-platelet interactions as novel treatment targets in cardiovascular disease
Neutrophils and platelets are among the most abundant cell types in peripheral blood and
characterized by high plasticity and a readily available reservoir of surface proteins and …
characterized by high plasticity and a readily available reservoir of surface proteins and …
Platelet–Neutrophil Crosstalk in Thrombosis
LJ Mereweather, A Constantinescu-Bercu… - International journal of …, 2023 - mdpi.com
Platelets are essential for the formation of a haemostatic plug to prevent bleeding, while
neutrophils are the guardians of our immune defences against invading pathogens. The …
neutrophils are the guardians of our immune defences against invading pathogens. The …
Neutrophils in cardiovascular disease: warmongers, peacemakers, or both?
G Sreejit, J Johnson, RM Jaggers… - Cardiovascular …, 2022 - academic.oup.com
Neutrophils, the most abundant of all leucocytes and the first cells to arrive at the sites of
sterile inflammation/injury act as a double-edged sword. On one hand, they inflict a …
sterile inflammation/injury act as a double-edged sword. On one hand, they inflict a …
Platelet–neutrophil interactions as drivers of inflammatory and thrombotic disease
T Lisman - Cell and tissue research, 2018 - Springer
Neutrophils are well known for their role in infection and inflammatory disease and are first
responders at sites of infection or injury. Platelets have an established role in hemostasis …
responders at sites of infection or injury. Platelets have an established role in hemostasis …
[HTML][HTML] Role of neutrophils, platelets, and extracellular vesicles and their interactions in COVID‐19‐associated thrombopathy
The COVID‐19 pandemic extended all around the world causing millions of deaths. In
addition to acute respiratory distress syndrome, many patients with severe COVID‐19 …
addition to acute respiratory distress syndrome, many patients with severe COVID‐19 …
Misunderstandings between platelets and neutrophils build in chronic inflammation
GA Ramirez, AA Manfredi, N Maugeri - Frontiers in immunology, 2019 - frontiersin.org
Regulated hemostasis, inflammation and innate immunity entail extensive interactions
between platelets and neutrophils. Under physiological conditions, vascular inflammation …
between platelets and neutrophils. Under physiological conditions, vascular inflammation …
Platelets in atherothrombosis: new and evolving roles
A Weyrich, F Cipollone, A Mezzetti… - Current …, 2007 - ingentaconnect.com
The functional interplay of platelets with leukocytes and endothelial cells is critical both in
physiological conditions, such as host defense, wound repair and tissue healing, and in …
physiological conditions, such as host defense, wound repair and tissue healing, and in …
Platelet-neutrophil interplay: insights into neutrophil extracellular trap (NET)-driven coagulation in infection
AZ Zucoloto, CN Jenne - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Well established for their central role in hemostasis, platelets have increasingly been
appreciated as immune cells in recent years. This emerging role should not come as a …
appreciated as immune cells in recent years. This emerging role should not come as a …
Immunothrombosis and thromboinflammation in host defense and disease
K Martinod, C Deppermann - Platelets, 2021 - Taylor & Francis
Platelets are increasingly being recognized for playing roles beyond thrombosis and
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …
Platelets in neutrophil recruitment to sites of inflammation
Recent findings have contributed to our burgeoning understanding of the platelet-dependent
mechanisms that control neutrophil recruitment to sites of inflammation and have opened up …
mechanisms that control neutrophil recruitment to sites of inflammation and have opened up …