TNF-α-mediated endothelial cell apoptosis is rescued by hydrogen sulfide

L Diaz Sanchez, L Sanchez-Aranguren, K Wang… - Antioxidants, 2023 - mdpi.com
Highlights Hydrogen sulfide ameliorates TNF-α mediated endothelial dysfunction in human
endothelial cells by regulating the intrinsic apoptosis pathway. Beneficial effects of hydrogen …

Hydrogen sulfide and endothelial dysfunction: relationship with nitric oxide

Z Altaany, F Moccia, L Munaron… - Current medicinal …, 2014 - ingentaconnect.com
The endothelium is a cellular monolayer that lines the inner surface of blood vessels and
plays a central role in the maintenance of cardiovascular homeostasis by controlling platelet …

Hydrogen sulfide protects against high-glucose–induced apoptosis in endothelial cells

Q Guan, Y Zhang, C Yu, Y Liu, L Gao… - Journal of …, 2012 - journals.lww.com
Hydrogen sulfide (H 2 S) is the third endogenous gaseous mediator identified after nitric
oxide and carbon monoxide. It has been demonstrated that H 2 S has protective effects on …

[HTML][HTML] Hydrogen sulfide and vascular regulation–An update

B Lv, S Chen, C Tang, H Jin, J Du, Y Huang - Journal of advanced research, 2021 - Elsevier
Abstract Background Hydrogen sulfide (H 2 S) is considered to be the third gasotransmitter
after carbon monoxide (CO) and nitric oxide (NO). It plays an important role in the regulation …

Role of endothelial dysfunction in cardiovascular diseases: the link between inflammation and hydrogen sulfide

HJ Sun, ZY Wu, XW Nie, JS Bian - Frontiers in pharmacology, 2020 - frontiersin.org
Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Modulation of hydrogen sulfide by vascular hypoxia

JM Osmond, NL Kanagy - Hypoxia, 2014 - Taylor & Francis
Hydrogen sulfide (H2S) has emerged as a key regulator of cardiovascular function. This
gasotransmitter is produced in the vasculature and is involved in numerous processes that …

[HTML][HTML] Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches

V Citi, A Martelli, E Gorica, S Brogi, L Testai… - Journal of advanced …, 2021 - Elsevier
Background The vascular endothelium represents a fundamental mechanical and biological
barrier for the maintenance of vascular homeostasis along the entire vascular tree. Changes …

The role of H2S bioavailability in endothelial dysfunction

R Wang, C Szabo, F Ichinose, A Ahmed… - Trends in …, 2015 - cell.com
Endothelial dysfunction (EDF) reflects pathophysiological changes in the phenotype and
functions of endothelial cells that result from and/or contribute to a plethora of cardiovascular …

Downregulation of endogenous hydrogen sulfide pathway is involved in mitochondrion‐related endothelial cell apoptosis induced by high salt

Y Zong, Y Huang, S Chen, M Zhu… - Oxidative Medicine …, 2015 - Wiley Online Library
Background. The study aimed to investigate whether endogenous H2S pathway was
involved in high‐salt‐stimulated mitochondria‐related vascular endothelial cell (VEC) …

Hydrogen sulfide: A new therapeutic target in vascular diseases

C Zhu, Q Liu, X Li, R Wei, T Ge, X Zheng, B Li… - Frontiers in …, 2022 - frontiersin.org
Hydrogen sulfide (H2S) is one of most important gas transmitters. H2S modulates many
physiological and pathological processes such as inflammation, oxidative stress and cell …