Suicide and major depressive disorder (MDD) are complex conditions that almost certainly
arise from the influences of many interrelated factors. There are significant regional …

Abstract Reno, Elaine, Talia L. Brown, Marian E. Betz, Michael H. Allen, Lilian Hoffecker,
Jeremy Reitinger, Robert Roach, and Benjamin Honigman. Suicide and high altitude: an …

Hypoxia is characteristic of living at high altitude. Animal and human studies have shown
that chronic hypoxia is associated with changes in the brain. Neurological symptoms are …

Over sixteen million people suffer from a depressive episode annually in the United States,
with females affected at twice the rate of males. Little is known about the effects of exposure …

Suicide rates are higher at high altitudes; some hypothesize that hypoxia is the cause. We
examined 8,871 suicides recorded in 2006 in 15 states by the National Violent Death …

In the United States, suicide rates consistently vary among geographic regions; the western
states have significantly higher suicide rates than the eastern states. The reason for this …

Abstract Kanekar, Shami, Olena V. Bogdanova, Paul R. Olson, Young-Hoon Sung, Kristen E.
D'Anci, and Perry F. Renshaw. Hypobaric hypoxia induces depression-like behavior in …

Objective: The authors recently observed a correlation between state altitude and suicide
rate in the United States, which could be explained by higher rates of gun ownership and …

Residing at high altitude may lead to reduced blood oxygen saturation in the brain and
altered metabolism in frontal cortical brain areas, probably due to chronic hypobaric …

Abstract Sheth, Chandni, Hendrik Ombach, Paul Olson, Perry F. Renshaw, and Shami
Kanekar. Increased anxiety and anhedonia in female rats following exposure to altitude …