Improving bioinformatics prediction of microRNA targets by ranks aggregation

A Quillet, C Saad, G Ferry, Y Anouar, N Vergne… - Frontiers in …, 2020 - frontiersin.org
microRNAs are noncoding RNAs which downregulate a large number of target mRNAs and
modulate cell activity. Despite continued progress, bioinformatics prediction of microRNA …

mirDIP 4.1—integrative database of human microRNA target predictions

T Tokar, C Pastrello, AEM Rossos… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

Accurate microRNA target prediction correlates with protein repression levels

M Maragkakis, P Alexiou, GL Papadopoulos… - BMC …, 2009 - Springer
Background MicroRNAs are small endogenously expressed non-coding RNA molecules
that regulate target gene expression through translation repression or messenger RNA …

miRDB: an online database for prediction of functional microRNA targets

Y Chen, X Wang - Nucleic acids research, 2020 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that act as master regulators in many
biological processes. miRNAs function mainly by downregulating the expression of their …

Improving microRNA target prediction with gene expression profiles

C Ovando-Vázquez, D Lepe-Soltero, C Abreu-Goodger - BMC genomics, 2016 - Springer
Background Mammalian genomes encode for thousands of microRNAs, which can
potentially regulate the majority of protein-coding genes. They have been implicated in …

Improving performance of mammalian microRNA target prediction

H Liu, D Yue, Y Chen, SJ Gao, Y Huang - BMC bioinformatics, 2010 - Springer
Background MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate
a wide range of cellular processes by silencing the gene expression at the protein and/or …

miRmap web: comprehensive microRNA target prediction online

CE Vejnar, M Blum, EM Zdobnov - Nucleic acids research, 2013 - academic.oup.com
MicroRNAs (miRNAs) posttranscriptionally repress the expression of protein-coding genes.
Based on the partial complementarity between miRNA and messenger RNA pairs with a …

miRSystem: an integrated system for characterizing enriched functions and pathways of microRNA targets

TP Lu, CY Lee, MH Tsai, YC Chiu, CK Hsiao, LC Lai… - 2012 - journals.plos.org
Background Many prediction tools for microRNA (miRNA) targets have been developed, but
inconsistent predictions were observed across multiple algorithms, which can make further …

Comparison and integration of target prediction algorithms for microRNA studies

Y Zhang, FJ Verbeek - Journal of integrative bioinformatics, 2010 - degruyter.com
Summary microRNAs are short RNA fragments that have the capacity of regulating
hundreds of target gene expression. Currently, due to lack of high-throughput experimental …

Computational prediction of microRNA target genes, target prediction databases, and web resources

JT Roberts, GM Borchert - Bioinformatics in microRNA research, 2017 - Springer
MicroRNA (miRNA) mediated silencing and repression of mRNA molecules requires
complementary base pairing between the “seed” region of the miRNA and the “seed match” …