Macrophages, an important component of the innate immune response, are a key regulator
of intestinal microenvironment homeostasis. These cells essentially contribute to chronic …

Ulcerative colitis (UC), a type of inflammatory bowel disease characterized by recurring and
incurable symptoms, causes immense suffering and economic burden for patients due to the …

Intestinal macrophages are the main participants of intestinal immune homeostasis and
intestinal inflammation. Under different environmental stimuli, intestinal macrophages can …

Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is a
refractory disease with many immune abnormalities and pathologies in the gastrointestinal …

The common and frequent disease, ulcerative colitis (UC), causes serious physical and
mental distress to patients. M2 macrophages have proven to play a role in anti-inflammation …

Ulcerative colitis (UC) is featured with relapsing inflammation in the colon, where
macrophages are recruited and polarized locally into M1 type to drive further inflammation …

Macrophages are part of the innate immunity and are key players for the maintenance of
intestinal homeostasis. They belong to the group of mononuclear phagocytes, which exert …

Ulcerative colitis (UC) is an idiopathic relapsing inflammatory disease. Although the etiology
of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa …

Ulcerative colitis is a chronic inflammatory condition of the large intestine whose etiology
remains largely unknown. Its pathogenesis involves the breakdown of intestinal mucosal …

Combination therapy is an emerging strategy that is under intensive preclinical investigation
for the treatment of various diseases. CD98 is highly overexpressed on the surfaces of …