Side effects of inhaled corticosteroids

JH Toogood - Journal of allergy and clinical immunology, 1998 - Elsevier
Inhaled corticosteroid (ICS) therapy carries less risk of complicating drug-or disease-related
morbidity and mortality than that associated with other antiasthmatic drugs such as …

Establishing a therapeutic index for the inhaled corticosteroids: Part II: Comparisons of systemic activity and safety among different inhaled corticosteroids

CA Sorkness - Journal of allergy and clinical immunology, 1998 - Elsevier
The systemic activity and safety of inhaled corticosteroids are best studied in randomized,
controlled, long-term trials with clinically relevant doses in subjects. These studies require …

Dose response to inhaled corticosteroids: benefits and risks

BJ Lipworth, AM Wilson - Seminars in respiratory and critical …, 1998 - thieme-connect.com
The therapeutic ratio for inhaled corticosteroid therapy is determined by the relative dose-
response relationships for anti-asthmatic clinical efficacy and systemic adverse effects. In …

Potential adverse effects of the inhaled corticosteroids

HW Kelly, HS Nelson - Journal of Allergy and Clinical Immunology, 2003 - Elsevier
The purpose of this review is to provide the clinician with an update on the potential adverse
effects caused by the inhaled corticosteroids (ICSs). The systemic effects of ICSs are a result …

Inhaled corticosteroids: past lessons and future issues

DB Allen, L Bielory, H Derendorf, R Dluhy… - Journal of Allergy and …, 2003 - Elsevier
Inhaled corticosteroids play a pivotal role in the treatment of asthma. Inhalation permits
effective delivery of the corticosteroid in high concentration to target sites within the lung …

Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials

S Pedersen - Drug safety, 2006 - Springer
Inhaled corticosteroids are established as the mainstay of maintenance therapy for chronic
asthma. However, there remains some debate regarding the safety of long-term use of these …

Safety of high-dose inhaled corticosteroids

NC Barnes - Respiratory medicine, 1993 - Elsevier
Inhaled corticosteroids are being given to more patients, at increasing doses and for longer
periods of time. This has led to renewed concern about side-effects, particularly when higher …

Adverse effects of inhaled corticosteroids

NA Hanania, KR Chapman, S Kesten - The American journal of medicine, 1995 - Elsevier
Inhaled corticosteroids are considered by many to be the anti-inflammatory therapy of choice
in adult asthma, given their remarkable efficacy and apparent safety. They are presently …

Effects of inhaled steroids on growth, bone metabolism and adrenal function

DB Allen - Expert review of respiratory medicine, 2007 - Taylor & Francis
Inhaled corticosteroids are a first-line therapy for persistent asthma in children. Major safety
concerns of long-term inhaled corticosteroid therapy include suppression of adrenal …

The properties of inhaled corticosteroids: similarities and differences

NC Barnes - Primary Care Respiratory Journal, 2007 - nature.com
Inhaled corticosteroids remain the most important therapy for chronic asthma in both adults
and children. As all inhaled corticosteroids act by binding to a common glucocorticoid …