Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2023 - mdpi.com
Scutellaria baicalensis Georgi (SBG), an herbal medicine with various biological activities,
including anti-inflammatory, anticancer, antiviral, antibacterial, and antioxidant activities, is …

Chemical, Pharmacological and Computerized Molecular Analysis of Stem's Extracts of Bauhinia scandens L. Provide Insights into the Management of Diarrheal and …

MM Islam, R Alam, HJ Chung, NU Emon… - Nutrients, 2022 - mdpi.com
Bauhinia scandens L.(Family: Fabaceae) is commonly used to treat cholera, diarrhea,
asthma, and diabetes disorder in integrative medicine. This study aimed to screen the …

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis

ZL Wang, S Wang, Y Kuang, ZM Hu, X Qiao… - Pharmaceutical …, 2018 - Taylor & Francis
Abstract Context: Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant.
Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded …

Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade

S Zeng, L Chen, Q Sun, H Zhao, H Yang, S Ren… - European Journal of …, 2021 - Elsevier
Dysregulated Wnt/β-catenin signaling pathway plays a critical role in the pathogenesis of
colorectal cancer (CRC). Scutellarin, a flavonoid compound in Scutellaria barbata, has been …

Suppression of colitis-associated colorectal cancer by scutellarin through inhibiting Hedgehog signaling pathway activity

S Zeng, L Tan, Q Sun, L Chen, H Zhao, M Liu, H Yang… - Phytomedicine, 2022 - Elsevier
Background Colitis-associated colorectal cancer (CAC) is a specific type of colorectal cancer
(CRC) and mainly develops from long-term intestinal inflammation. Mounting evidence …

The pharmacological efficacy of baicalin in inflammatory diseases

Y Wen, Y Wang, C Zhao, B Zhao, J Wang - International Journal of …, 2023 - mdpi.com
Baicalin is one of the most abundant flavonoids found in the dried roots of Scutellaria
baicalensis Georgi (SBG) belonging to the genus Scutellaria. While baicalin is demonstrated …

Biomedical Applications of Scutellaria edelbergii Rech. f.: In Vitro and In Vivo Approach

M Shah, W Murad, N Ur Rehman, SA Halim, M Ahmed… - Molecules, 2021 - mdpi.com
In the current study, in vitro antimicrobial and antioxidant activities and in vivo anti-
inflammatory and analgesic activities of Scutellaria edelbergii Rech. f.(crude extract and …

Anticancer Activity of Scutellaria baicalensis and Its Potential Mechanism

F Ye, L Xui, J Yi, W Zhang, DY Zhang - The Journal of Alternative & …, 2002 - liebertpub.com
Objective: Scutellaria baicalensis is a widely used Chinese herbal medicine that historically
is used in anti-inflammatory and anticancer therapy. The aim of the study is to determine its …

Baicalin, a natural antimicrobial and anti-biofilm agent

MA Ozma, E Khodadadi, F Pakdel… - Journal of Herbal …, 2021 - Elsevier
The development of drug-resistant bacteria as a result of the inappropriate use of antibiotics,
has led to a study on other sources of drugs for the treatment of bacterial infections. Natural …

Chloroform fraction of Scutellaria barbata D. Don promotes apoptosis and suppresses proliferation in human colon cancer cells

L Zhang, Q Cai, J Lin, Y Fang… - Molecular …, 2014 - spandidos-publications.com
Abstract Scutellaria barbata D. Don (SB) has long been used as a major component in
numerous Chinese medical formulas to clinically treat various types of cancer. Previously …