Growing evidence shows that Baihu-Guizhi decoction (BHGZD), a traditional Chinese
medicine (TCM)-originated disease-modifying anti-rheumatic prescription, may exert a …

Gallic acid is an active phenolic acid widely distributed in plants, and there is compelling
evidence to prove its anti-inflammatory effects. NLRP3 inflammasome dysregulation is …

Rheumatoid arthritis is a systemic autoimmune disease characterized by chronic
inflammation of synovial joints, ultimately leading to a progressive and irreversible joint …

Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

Wu-tou decoction (WTD) has been extensively used for the treatment of rheumatoid arthritis
(RA). Due to lack of appropriate methods, pharmacological mechanisms of WTD acting on …

Background Thousands of years of clinical application of Wutou decoction (WTD) support its
reliable efficacy and safety in treating rheumatoid arthritis (RA). However, the underlying …

Background: Wutou Decoction (WTD), as a classic prescription, has been generally used to
treat rheumatoid arthritis (RA) for two thousand years in China. However, the potential …

Corilagin, a gallotannin, shows excellent antioxidant and anti‐inflammatory effects. The
NLRP3 inflammasome dysfunction has been implicated in a variety of inflammation …

Recent reports have demonstrated the role of phyto-constituents in modulating inflammatory
responses. Mangiferin isolated from Mangifera indica is known to induce potent anti …

Rheumatoid arthritis (RA) is a common chronic autoimmune joint disease characteristic of
elevated proliferation and infiltration of fibroblast-like synoviocytes (FLS). Here, we aimed to …