Lipoprotein (a) and cardiovascular disease

PR Kamstrup - Clinical chemistry, 2021 - academic.oup.com
Background High lipoprotein (a) concentrations present in 10%–20% of the population have
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …

Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options

A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
Abstract Lipoprotein (a)(Lp (a)) was discovered more than 50 years ago, and a decade later,
it was recognized as a risk factor for coronary artery disease. However, it has gained …

Use of Lipoprotein (a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association

DP Wilson, TA Jacobson, PH Jones… - Journal of clinical …, 2019 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a well-recognized, independent risk factor for
atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

Lipoprotein (a) and cardiovascular disease: prediction, attributable risk fraction, and estimating benefits from novel interventions

P Welsh, C Welsh, CA Celis-Morales… - European Journal of …, 2021 - academic.oup.com
Aims To investigate the population attributable fraction due to elevated lipoprotein (a)(Lp (a))
and the utility of measuring Lp (a) in cardiovascular disease (CVD) risk prediction. Methods …

Lipoprotein (a) and cardiovascular and valvular diseases: a genetic epidemiological perspective

BJ Arsenault, PR Kamstrup - Atherosclerosis, 2022 - Elsevier
Rates of atherosclerotic cardiovascular diseases (CVD) in the Western world have
spectacularly decreased over the past 50 years. However, a substantial proportion of high …

Lipoprotein (a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop …

S Tsimikas, JL Hall - Journal of the American College of Cardiology, 2012 - jacc.org
Recent published studies have provided increasing evidence that lipoprotein (a)[Lp (a)] may
be a potential causal, genetic, independent risk factor for cardiovascular disease (CVD). Lp …

Lipoprotein (a) levels in a global population with established atherosclerotic cardiovascular disease

SE Nissen, K Wolski, L Cho, SJ Nicholls… - Open …, 2022 - openheart.bmj.com
Objective Lipoprotein (a)(Lp (a)) is an important genetically determined risk factor for
atherosclerotic vascular disease (ASCVD). With the development of Lp (a)-lowering …

Lipoprotein (a) and ischemic heart disease—a causal association? A review

PR Kamstrup - Atherosclerosis, 2010 - Elsevier
The aim of this review is to summarize present evidence of a causal association of
lipoprotein (a) with risk of ischemic heart disease (IHD). Evidence for causality includes …

Lipoprotein (a): a risk factor for atherosclerosis and an emerging therapeutic target

SA Di Fusco, M Arca, P Scicchitano, A Alonzo… - Heart, 2023 - heart.bmj.com
Lipoprotein (a)(Lp (a)) is a complex circulating lipoprotein, and increasing evidence has
demonstrated its role as a risk factor for atherosclerotic cardiovascular disease (ASCVD) …