Taste receptors in innate immunity

RJ Lee, NA Cohen - Cellular and molecular life sciences, 2015 - Springer
Taste receptors were first identified on the tongue, where they initiate a signaling pathway
that communicates information to the brain about the nutrient content or potential toxicity of …

Role of taste receptors as sentinels of innate immunity in the upper airway

NN Patel, AD Workman, NA Cohen - Journal of pathogens, 2018 - Wiley Online Library
Evidence is emerging that shows taste receptors serve functions outside of taste sensation
of the tongue. Taste receptors have been found in tissue across the human body, including …

Taste receptors in upper airway innate immunity

RM Carey, RJ Lee - Nutrients, 2019 - mdpi.com
Taste receptors, first identified on the tongue, are best known for their role in guiding our
dietary preferences. The expression of taste receptors for umami, sweet, and bitter have …

Role of taste receptors in innate immunity and oral health

R Xi, X Zheng, M Tizzano - Journal of Dental Research, 2022 - journals.sagepub.com
Taste receptors are receptor proteins that detect ligands belonging to the 5 taste modalities:
sweet, bitter, sour, salty, and umami. Taste receptors are not restricted to taste cells in taste …

Taste receptors: regulators of sinonasal innate immunity

RM Carey, ND Adappa, JN Palmer… - Laryngoscope …, 2016 - Wiley Online Library
Taste receptors in the oral cavity guide our preferences for foods, preventing toxic ingestions
and encouraging proper nutrient consumption. More recently, expression of taste receptors …

The role of bitter and sweet taste receptors in upper airway immunity

AD Workman, JN Palmer, ND Adappa… - Current Allergy and …, 2015 - Springer
Over the past several years, taste receptors have emerged as key players in the regulation
of innate immune defenses in the mammalian respiratory tract. Several cell types in the …

Bitter and sweet taste receptors in the respiratory epithelium in health and disease

RJ Lee, NA Cohen - Journal of molecular medicine, 2014 - Springer
Taste receptors on the tongue communicate information to the brain about the nutrient
content or potential toxicity of ingested foods. However, recent research has now shown that …

Chemosensors in the nose: guardians of the airways

M Tizzano, TE Finger - Physiology, 2013 - journals.physiology.org
The G-protein-coupled receptor molecules and downstream effectors that are used by taste
buds to detect sweet, bitter, and savory tastes are also utilized by chemoresponsive cells of …

[HTML][HTML] Taste isn't just for taste buds anymore

TE Finger, SC Kinnamon - F1000 biology reports, 2011 - ncbi.nlm.nih.gov
Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste
buds) and at least two distinct families of G protein-coupled receptor molecules that detect …

The role of bitter and sweet taste receptors in upper airway innate immunity: recent advances and future directions

IW Maina, AD Workman, NA Cohen - World journal of …, 2018 - mednexus.org
Bitter (T2R) and sweet (T1R) taste receptors have been implicated in sinonasal innate
immunity and in the pathophysiology of chronic rhinosinusitis (CRS). Taste receptors are …