Progress and potential in organoid research
G Rossi, A Manfrin, MP Lutolf - Nature Reviews Genetics, 2018 - nature.com
Tissue and organ biology are very challenging to study in mammals, and progress can be
hindered, particularly in humans, by sample accessibility and ethical concerns. However …
hindered, particularly in humans, by sample accessibility and ethical concerns. However …
Genetic engineering in organoids
I Teriyapirom, AS Batista-Rocha, BK Koo - Journal of Molecular Medicine, 2021 - Springer
Three-dimensional organoids have been widely used for developmental and disease
modeling. Organoids are derived from both adult and pluripotent stem cells. Various types …
modeling. Organoids are derived from both adult and pluripotent stem cells. Various types …
A brief history of organoids
C Corrò, L Novellasdemunt… - American Journal of …, 2020 - journals.physiology.org
In vitro cell cultures are crucial research tools for modeling human development and
diseases. Although the conventional monolayer cell cultures have been widely used in the …
diseases. Although the conventional monolayer cell cultures have been widely used in the …
Primary human organoids models: Current progress and key milestones
During the past 10 years the world has experienced enormous progress in the organoids
field. Human organoids have shown huge potential to study organ development …
field. Human organoids have shown huge potential to study organ development …
Organoids: The current status and biomedical applications
S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
Human organoids in basic research and clinical applications
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
Biologically inspired approaches to enhance human organoid complexity
EM Holloway, MM Capeling, JR Spence - Development, 2019 - journals.biologists.com
Organoids are complex three-dimensional in vitro organ-like model systems. Human
organoids, which are derived from human pluripotent stem cells or primary human donor …
organoids, which are derived from human pluripotent stem cells or primary human donor …
Organoid models and applications in biomedical research
C Xinaris, V Brizi, G Remuzzi - Nephron, 2015 - karger.com
Recent technical advances in the stem cell field have enabled the in vitro generation of
complex structures resembling whole organs termed organoids. Most of these approaches …
complex structures resembling whole organs termed organoids. Most of these approaches …
Organoid technology for tissue engineering
J He, X Zhang, X Xia, M Han, F Li, C Li… - Journal of Molecular …, 2020 - academic.oup.com
For centuries, attempts have been continuously made to artificially reconstitute counterparts
of in vivo organs from their tissues or cells. Only in the recent decade has organoid …
of in vivo organs from their tissues or cells. Only in the recent decade has organoid …