Disruption of circadian rhythm and risk of autism spectrum disorder: role of immune-inflammatory, oxidative stress, metabolic and neurotransmitter pathways

F Abdul, N Sreenivas, JVS Kommu… - Reviews in the …, 2022 - degruyter.com
Circadian rhythms in most living organisms are regulated by light and synchronized to an
endogenous biological clock. The circadian clock machinery is also critically involved in …

Biological timing and neurodevelopmental disorders: a role for circadian dysfunction in autism spectrum disorders

E Lorsung, R Karthikeyan, R Cao - Frontiers in Neuroscience, 2021 - frontiersin.org
Autism spectrum disorders (ASDs) are a spectrum of neurodevelopmental disorders
characterized by impaired social interaction and communication, as well as stereotyped and …

Dysregulation of circadian rhythms in autism spectrum disorders

L Pinato, CS Galina Spilla, RP Markus… - Current …, 2019 - ingentaconnect.com
Background: The alterations in neurological and neuroendocrine functions observed in the
autism spectrum disorder (ASD) involves environmentally dependent dysregulation of …

Are circadian rhythms new pathways to understand Autism Spectrum Disorder?

MM Geoffray, A Nicolas, M Speranza… - Journal of Physiology …, 2016 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a frequent neurodevelopmental disorder. ASD
is probably the result of intricate interactions between genes and environment altering …

Rhythms of life: circadian disruption and brain disorders across the lifespan

RW Logan, CA McClung - Nature Reviews Neuroscience, 2019 - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Disruption of circadian rhythms by ambient light during neurodevelopment leads to autistic-like molecular and behavioral alterations in adult mice

K Fang, D Liu, SS Pathak, B Yang, J Li, R Karthikeyan… - Cells, 2021 - mdpi.com
Although circadian rhythms are thought to be essential for maintaining body health, the
effects of chronic circadian disruption during neurodevelopment remain elusive. Here, using …

Biological correlates of altered circadian rhythms, autonomic functions and sleep problems in autism spectrum disorder

L Dell'Osso, L Massoni, S Battaglini… - Annals of General …, 2022 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by a
complex and multifaceted neurobehavioral syndrome. In the last decades, several studies …

Disrupted circadian rhythm as a common player in developmental models of neuropsychiatric disorders

EM Marco, E Velarde, R Llorente, G Laviola - Neurotoxin Modeling of Brain …, 2016 - Springer
The environment in which individuals develop and mature is critical for their physiological
and psychological outcome; in particular, the intrauterine environment has reached far more …

Links between circadian rhythms and psychiatric disease

IN Karatsoreos - Frontiers in behavioral neuroscience, 2014 - frontiersin.org
Determining the cause of psychiatric disorders is a goal of modern neuroscience, and will
hopefully lead to the discovery of treatments to either prevent or alleviate the suffering …

Circadian rhythms and sleep in children with autism

G Glickman - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
A growing body of research has identified significant sleep problems in children with autism.
Disturbed sleep–wake patterns and abnormal hormone profiles in children with autism …