New views on cellular uptake and trafficking of manufactured nanoparticles

L Treuel, X Jiang, GU Nienhaus - Journal of the Royal …, 2013 - royalsocietypublishing.org
Nanoparticles (NPs) are of similar size to typical cellular components and proteins, and can
efficiently intrude living cells. A detailed understanding of the involved processes at the …

[HTML][HTML] Nanoparticle interactions with live cells: quantitative fluorescence microscopy of nanoparticle size effects

L Shang, K Nienhaus, X Jiang, L Yang… - Beilstein journal of …, 2014 - beilstein-journals.org
Engineered nanomaterials are known to enter human cells, often via active endocytosis.
Mechanistic details of the interactions between nanoparticles (NPs) with cells are still not …

Nanoparticle entry into cells; the cell biology weak link

G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Rapid internalization of nanoparticles by human cells at the single particle level

CJ Richards, TCQ Burgers, R Vlijm, WH Roos… - ACS …, 2023 - ACS Publications
Nanoparticle uptake by cells has been studied for applications both in nanomedicine and in
nanosafety. While the majority of studies have focused on the biological mechanisms …

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

L Liu, X Bai, MV Martikainen, A Kårlund… - Nature …, 2021 - nature.com
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …

It's what's on the inside that counts: Techniques for investigating the uptake and recycling of nanoparticles and proteins in cells

LI FitzGerald, APR Johnston - Journal of Colloid and Interface Science, 2021 - Elsevier
Many applications of nanomedicines depend on the therapeutic gaining access to the
interior of cells. As most proteins and nanoparticles are taken up by endocytosis …

Insights into cellular uptake of nanoparticles

M Hasanzadeh Kafshgari, FJ Harding… - Current drug …, 2015 - ingentaconnect.com
Nanomaterials promise to improve disease diagnosis and treatment by enhancing the
delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In …

Exocytosis of nanoparticles from cells: role in cellular retention and toxicity

R Sakhtianchi, RF Minchin, KB Lee, AM Alkilany… - Advances in colloid and …, 2013 - Elsevier
Over the past decade, nanoparticles (NPs) have been increasingly developed in various
biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug …

Brief update on endocytosis of nanomedicines

S Patel, J Kim, M Herrera, A Mukherjee… - Advanced drug delivery …, 2019 - Elsevier
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Endocytosis at the nanoscale

I Canton, G Battaglia - Chemical Society Reviews, 2012 - pubs.rsc.org
Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …