Serum TSH and risk of papillary thyroid cancer in nodular thyroid disease

E Fiore, P Vitti - The Journal of Clinical Endocrinology & …, 2012 - academic.oup.com
Context: TSH is the main factor involved in the control of proliferation of thyrocytes. Recently,
a strong relationship between serum TSH and risk of thyroid malignancy has been reported …

L-thyroxine-treated patients with nodular goiter have lower serum TSH and lower frequency of papillary thyroid cancer: results of a cross-sectional study on 27 914 …

E Fiore, T Rago, MA Provenzale… - Endocrine-related …, 2010 - erc.bioscientifica.com
The risk of papillary thyroid cancer (PTC) is related to serum TSH, and the development of
thyroid autonomy by reducing TSH levels decreases the frequency of PTC in patients with …

Lower levels of TSH are associated with a lower risk of papillary thyroid cancer in patients with thyroid nodular disease: thyroid autonomy may play a protective role

E Fiore, T Rago, MA Provenzale… - Endocrine-related …, 2009 - erc.bioscientifica.com
Higher TSH values, even within normal ranges, have been associated with a greater risk of
thyroid malignancy. The relationship between TSH and papillary thyroid cancer (PTC) has …

Higher TSH level is a risk factor for differentiated thyroid cancer

HK Kim, JH Yoon, SJ Kim, JS Cho… - Clinical …, 2013 - Wiley Online Library
Objectives Higher thyroid‐stimulating hormone (TSH) levels are associated with
differentiated thyroid cancers (DTC). To validate this association, we compared TSH levels …

The association between serum TSH concentration and thyroid cancer

K Boelaert - Endocrine-related cancer, 2009 - erc.bioscientifica.com
There is mounting evidence that the serum concentration of TSH is an independent predictor
for the diagnosis of thyroid malignancy in patients with nodular thyroid disease. Furthermore …

Higher serum TSH in thyroid cancer patients occurs independent of age and correlates with extrathyroidal extension

MR Haymart, SL Glinberg, J Liu, RS Sippel… - Clinical …, 2009 - Wiley Online Library
Background It has previously been shown that higher serum TSH is associated with
increased thyroid cancer incidence and advanced‐stage disease. In the healthy adult …

Serum TSH levels as a predictor of malignancy in thyroid nodules: A prospective study

L Golbert, AP de Cristo, CS Faccin, M Farenzena… - PloS one, 2017 - journals.plos.org
Background The role of serum TSH concentrations as a predictor of malignancy of thyroid
nodule remains unclear. Objective To prospectively evaluate the usefulness of serum TSH …

Thyrotropin and thyroid cancer diagnosis: a systematic review and dose-response meta-analysis

DSA McLeod, KF Watters, AD Carpenter… - The Journal of …, 2012 - academic.oup.com
Context: TSH is the major growth factor for thyrocytes and may have a causative role in
thyroid cancer. Objective: The objective of the study was to systematically assess the …

Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancer and advanced tumor stage

MR Haymart, DJ Repplinger… - The Journal of …, 2008 - academic.oup.com
Context: TSH is a known thyroid growth factor, but the pathogenic role of TSH in thyroid
oncogenesis is unclear. Objective: The aim was to examine the relationship between …

Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules

SA Polyzos, M Κita, Z Efstathiadou, P Poulakos… - Journal of cancer …, 2008 - Springer
Purpose Serum thyrotropin (TSH) is a well-established growth factor for thyroid nodules and
suppression of TSH concentrations by administering exogenous thyroxine may interfere with …