Interleukin 17A (IL-17A) is one of the currently known six members of the IL-17 cytokine
family and is implicated in immune responses to infectious pathogens and in the …

Psoriasis is a prevalent, chronic inflammatory disease of the skin mediated by cross-talk
occurring between epidermal keratinocytes, dermal vascular cells and immunocytes …

Psoriasis is a frequent chronic inflammatory skin disease, nowadays considered a major
global health problem. Several new drugs, targeting the IL-23/IL-17A pathway, have been …

Psoriasis is a chronic inflammatory skin condition associated with immune dysregulation.
The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically …

Psoriasis is a frequent, chronic disease characterized by cutaneous inflammatory plaques
and/or arthritis. It may be associated with few other diseases, mainly Crohn's disease and …

Psoriasis is a common chronic inflammatory skin disease, associated with substantial
comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived …

Psoriasis is an immune-mediated inflammatory skin disease associated with numerous
inflammatory comorbidities, including increased cardiovascular risk. The interleukin (IL) …

Nowadays, it is well established a link between psoriasis and cardiovascular (CV) diseases.
A series of different overlapping mechanisms including inflammation, homeostasis …

Alterations in the innate and adaptive immunity underpin psoriasis pathophysiology, with the
Th17 cells subset now recognized as the fundamental cells in the key controlling pathway …

In addition to being recognized as a chronic inflammatory disease that manifests in the skin,
psoriasis is increasingly understood to be a systemic disease that causes immune …