Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Tailoring therapies to counter the divergent immune landscapes of breast cancer

S Attalla, T Taifour, W Muller - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Breast cancer remains a significant clinical concern affecting millions of women worldwide.
Immunotherapy is a rapidly growing drug class that has revolutionized cancer treatment but …

Harnessing the immune system for the treatment of breast cancer

X Jiang - Journal of Zhejiang University Science B, 2014 - Springer
Standard treatment options for breast cancer include surgery, chemotherapy, radiation, and
targeted therapies, such as adjuvant hormonal therapy and monoclonal antibodies …

New insights into the role of the immune microenvironment in breast carcinoma

L de la Cruz-Merino, A Barco-Sánchez… - Journal of …, 2013 - Wiley Online Library
Recently, immune edition has been recognized as a new hallmark of cancer. In this respect,
some clinical trials in breast cancer have reported imppressive outcomes related to …

Cancer stem cell–immune cell crosstalk in breast tumor microenvironment: a determinant of therapeutic facet

A Guha, KK Goswami, J Sultana, N Ganguly… - Frontiers in …, 2023 - frontiersin.org
Breast cancer (BC) is globally one of the leading killers among women. Within a breast
tumor, a minor population of transformed cells accountable for drug resistance, survival, and …

Regulation of immunity in breast cancer

CA Edechi, N Ikeogu, JE Uzonna, Y Myal - Cancers, 2019 - mdpi.com
Breast cancer affects millions of women worldwide, leading to many deaths and significant
economic burden. Although there are numerous treatment options available, the huge …

Immune landscape of breast cancers

D Nagarajan, SEB McArdle - Biomedicines, 2018 - mdpi.com
Breast cancer is a very heterogeneous disease, both at a molecular and a histological level.
Five intrinsic subtypes were initially identified—Luminal-A, Luminal-B, HER2+, Triple …

[HTML][HTML] Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy

SK Deshmukh, SK Srivastava, T Poosarla… - Annals of …, 2019 - ncbi.nlm.nih.gov
Breast cancer is the most commonly diagnosed malignancy and a leading cause of cancer-
related death in women worldwide. It also exhibits pronounced racial disparities in terms of …

Cellular interactions in tumor microenvironment during breast cancer progression: new frontiers and implications for novel therapeutics

T Akinsipe, R Mohamedelhassan, A Akinpelu… - Frontiers in …, 2024 - frontiersin.org
The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …

[HTML][HTML] Tumor microenvironment of human breast cancer, and feline mammary carcinoma as a potential study model

C Nascimento, F Ferreira - Biochimica Et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
In recent years, the tumor microenvironment (TME) has been a research hotspot, as it is
composed of distinct cellular and non-cellular elements that may influence the diagnosis …