Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK …
C Fan, W Cai, M Ye, M Chen, Y Dai - Journal of Integrative Medicine, 2022 - Elsevier
Abstract Objective Qili Qiangxin (QLQX), a compound herbal medicine formula, is used
effectively to treat congestive heart failure in China. However, the molecular mechanisms of …
effectively to treat congestive heart failure in China. However, the molecular mechanisms of …
Qiliqiangxin attenuates oxidative stress-induced mitochondrion-dependent apoptosis in cardiomyocytes via PI3K/AKT/GSK3β signaling pathway
Q Zhao, H Li, L Chang, C Wei, Y Yin, H Bei… - Biological and …, 2019 - jstage.jst.go.jp
Qiliqiangxin capsule (QLQX) is a well-known traditional Chinese medicine that exhibits
cardioprotective effects in heart failure patients. However, it remains unclear whether and by …
cardioprotective effects in heart failure patients. However, it remains unclear whether and by …
Qi-Li-Qiang-Xin Alleviates Isoproterenol-Induced Myocardial Injury by Inhibiting Excessive Autophagy via Activating AKT/mTOR Pathway
C Fan, X Tang, M Ye, G Zhu, Y Dai, Z Yao… - Frontiers in …, 2019 - frontiersin.org
Background: Apoptosis and autophagy are two important patterns of cell death in the
process of heart failure. Qi-Li-Qiang-Xin (QLQX), a traditional Chinese medicine, has been …
process of heart failure. Qi-Li-Qiang-Xin (QLQX), a traditional Chinese medicine, has been …
Protective effect of Qiliqiangxin against Doxorubicin‐induced cardiomyopathy by suppressing excessive autophagy and apoptosis
Y Qin, C Lv, X Zhang, W Ruan, X Xu… - Cardiovascular …, 2022 - Wiley Online Library
Background. Doxorubicin (DOX) is one of the most potent and widely prescribed antitumor
agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to …
agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to …
Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin-mediated mitochondrial autophagy
J Zhou, Z Wang, Y He, X Luo, W Zhang, L Yu… - … Medicine and Therapies, 2020 - Springer
Background Qiliqiangxin (QLQX) is a preparation refined from a traditional Chinese
medicine compound. It plays an important role in protecting cardiac function after myocardial …
medicine compound. It plays an important role in protecting cardiac function after myocardial …
QSKL protects against myocardial apoptosis on heart failure via PI3K/Akt-p53 signaling pathway
H Chang, C Li, Q Wang, L Lu, Q Zhang, Y Zhang… - Scientific Reports, 2017 - nature.com
The ancient traditional Chinese medicine Qishenkeli (QSKL) is widely used in the treatment
of heart failure (HF) in China. Previous studies have shown that QSKL has definite effects on …
of heart failure (HF) in China. Previous studies have shown that QSKL has definite effects on …
Hongjingtian injection attenuates myocardial oxidative damage via promoting autophagy and inhibiting apoptosis
S Zhang, L Zhang, H Zhang, G Fan… - Oxidative Medicine …, 2017 - Wiley Online Library
Natural products with antioxidative activities are widely applied to prevent and treat various
oxidative stress related diseases, including ischemic heart disease. However, the cellular …
oxidative stress related diseases, including ischemic heart disease. However, the cellular …
XuefuZhuyu decoction protected cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
X Shi, H Zhu, Y Zhang, M Zhou, D Tang… - BMC Complementary and …, 2017 - Springer
Background XuefuZhuyu decoction (XFZY) is a well-known traditional Chinese herbal
medicine for the treatment of various cardiovascular diseases, such as unstable angina …
medicine for the treatment of various cardiovascular diseases, such as unstable angina …
[HTML][HTML] Qiliqiangxin protects against cardiac ischemia-reperfusion injury via activation of the mTOR pathway
Y Zhou, H Fang, S Lin, S Shen, L Tao, J Xiao… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Qiliqiangxin (QL) has been used for the treatment of chronic heart failure
in China. Accumulating evidence suggests QL's cardio-protective effects on continuous …
in China. Accumulating evidence suggests QL's cardio-protective effects on continuous …
[HTML][HTML] Qiliqiangxin prevents right ventricular remodeling by inhibiting apoptosis and improving metabolism reprogramming with pulmonary arterial hypertension
Y Lu, J Wu, Y Sun, L Xin, Z Jiang, H Lin… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Pathological remodeling of the right ventricular (RV) contributes to the mortality of pulmonary
arterial hypertension (PAH) patients, and RV myocardial apoptosis and metabolism play …
arterial hypertension (PAH) patients, and RV myocardial apoptosis and metabolism play …