In recent years, RNA has emerged as a multifaceted biomolecule that is involved in virtually
every function of the cell and is critical for human health. This has led to a substantial …

Remarkable findings have cemented the central dogma of biology, where the transfer of
genetic information from a sequence of nucleotides in DNA to a string of amino acids in …

RNA–protein interactions influence many biological processes. Identifying the binding sites
of RNA-binding proteins (RBPs) remains one of the most fundamental and important …

The development of innovative methodologies to identify RNA binders has attracted
enormous attention in chemical biology and drug discovery. Although antibiotics targeting …

Protein–RNA interactions regulate RNA fate and function, and defects can lead to various
disorders. Such interactions have mainly been studied by nucleoside-based UV crosslinking …

Computational methods play a pivotal role in the early stages of small molecule drug
discovery and are widely applied in virtual screening, structure optimization, and compound …

Characterization of RNA–protein interaction is fundamental for understanding the
metabolism and function of RNA. UV crosslinking has been widely used to map the targets …

Modern organic chemistry enables practitioners of the art to controllably synthesize an
enormous array of structures with diverse molecular architectures, functional group …

A considerable amount of attention has focused recently on new RNA-binding molecules.
The interactions between RNA and biological macromolecules are clearly essential for …

In recent years, RNA has gained traction both as a therapeutic molecule and as a
therapeutic target in several human pathologies. In this review, we consider the approach of …